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Time-course gait pattern analysis in a rat model of foot drop induced by ventral root avulsion injury.
Author: ChanShu-Yen, ChangMing-Yuan, HsiehTsung-Hsun, KuoChi-Wei, LiaoTsai-Tsen, PengChih-Wei
Original Abstract of the Article :
Foot drop is a common clinical gait impairment characterized by the inability to raise the foot or toes during walking due to the weakness of the dorsiflexors of the foot. Lumbar spine disorders are common neurogenic causes of foot drop. The accurate prognosis and treatment protocols of foot drop ar...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806139/
データ提供:米国国立医学図書館(NLM)
Foot Drop: A Walk in the Desert of Gait Impairment
Foot drop is a common gait impairment characterized by difficulty lifting the foot during walking. This condition can be caused by various factors, including nerve injuries. This study aimed to develop a rat model of foot drop induced by ventral root avulsion (VRA) injury, a type of nerve injury. The researchers performed VRA surgery on rats and analyzed their gait patterns using video-based gait analysis. The study found that rats with L5 + L6 VRA exhibited significant gait impairments, including reduced walking speed, step length, and swing phase time, as well as increased stance phase time. These impairments were evident as early as the first day after surgery and gradually recovered over time.
Modeling Foot Drop: A Stepping Stone for Understanding and Treatment
This study provides a valuable animal model for investigating the mechanisms and recovery processes of foot drop. The results highlight the potential for using this model to develop and test new therapeutic strategies for this debilitating condition.
Understanding Gait Abnormalities: A Guide to Treatment
This research underscores the importance of understanding the complex interplay between nerve injuries and gait impairments. The study provides valuable insights into the temporal changes in gait patterns following VRA injury, paving the way for more effective treatment strategies.
Dr. Camel's Conclusion
This study provides a valuable animal model for understanding foot drop. It's like studying the footprints of a camel in the desert—each step reveals valuable information about the animal's journey. By understanding the mechanisms of foot drop, we can develop better treatments for this condition.
Date :
- Date Completed n.d.
- Date Revised 2023-01-11
Further Info :
Related Literature
English
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