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Current evidence for adjunct pyridoxine (vitamin B6) for the treatment of behavioral adverse effects associated with levetiracetam: A systematic review.

Author: BesagFrank M C, SenArjune, VaseyMichael J

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Pyridoxine (vitamin B6) supplementation may improve neuropsychiatric adverse events associated with levetiracetam, but more research is needed.
Paper Details　
Original Abstract of the Article :
Label="BACKGROUND">Levetiracetam (LVT), while an effective treatment for multiple seizure types, is associated with a high incidence of neuropsychiatric adverse events (NPAEs). In predominantly retrospective studies, supplementation with pyridoxine/vitamin B<sub>6</sub> (PN) was associated with impr...See full text at original site
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引用元：
https://doi.org/10.1016/j.yebeh.2022.109065

データ提供：米国国立医学図書館（NLM）

Levetiracetam Side Effects: Vitamin B6 as a Potential Solution?

Levetiracetam (LVT) is a powerful tool for managing seizures, but like a desert mirage, it can sometimes create side effects, particularly neuropsychiatric adverse events (NPAEs). This review delves into the potential role of pyridoxine, better known as vitamin B6, in alleviating these side effects.

Vitamin B6 Shows Promise in Reducing Levetiracetam Side Effects

While research on this topic is still developing, the review suggests that vitamin B6 supplementation may be helpful in reducing NPAEs associated with LVT. Although more double-blind, controlled studies are needed, the evidence currently available encourages further investigation of vitamin B6 as a potential treatment for these side effects.

Vitamin B6: A Natural Helper

Vitamin B6 is a vital nutrient, like a hidden spring in the desert, supporting various bodily functions, including brain health. This research suggests it might play a role in easing the side effects of LVT, but more studies are needed to confirm its effectiveness.

Dr.Camel's Conclusion

While LVT is a valuable tool for managing seizures, the possibility of side effects is a concern. This review suggests that vitamin B6 may offer a potential solution, but more research is crucial to confirm its effectiveness. As a wise camel, I believe in the power of natural solutions, and vitamin B6 deserves further exploration for its potential to enhance brain health and well-being.

Date :
  1. Date Completed 2023-03-10
  2. Date Revised 2023-03-22
Further Info :

Pubmed ID

36791631

DOI: Digital Object Identifier

10.1016/j.yebeh.2022.109065

SNS
PICO Info
in preparation
Languages

English

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