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Progress in pharmacotherapy for the treatment of hyperphosphatemia in renal failure.

Author: CalabreseVincenzo, CasuscelliChiara, CernaroValeria, Di CarloSilvia, GembilloGuido, LonghitanoElisa, SantoroDomenico, SpinellaClaudia

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

CKD-mineral bone disorder (CKD-MBD) is a significant complication of chronic kidney disease (CKD) contributing to morbidity and mortality. While hyperphosphatemia is common in advanced CKD, abnormalities in calcium/phosphate metabolism can occur in the early stages.
Paper Details　
Original Abstract of the Article :
Among the clinical and metabolic complications of progressive chronic kidney disease (CKD), CKD-mineral bone disorder (CKD-MBD) significantly contributes to morbidity and mortality. While overt and persistent hyperphosphatemia is typical of advanced CKD and requires treatment, other abnormalities of...See full text at original site
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引用元：
https://doi.org/10.1080/14656566.2023.2243817

データ提供：米国国立医学図書館（NLM）

Navigating the Challenges of Hyperphosphatemia in Renal Failure

Chronic kidney disease (CKD) is a formidable challenge, impacting millions of individuals worldwide. It's a condition that often progresses silently, with subtle changes in the body's delicate balance of minerals. One of the most significant complications of CKD is hyperphosphatemia, a condition characterized by high levels of phosphate in the blood. This article delves into the complexities of hyperphosphatemia and its impact on individuals with CKD, exploring current pharmacotherapy approaches to manage this condition.

Managing Hyperphosphatemia: A Delicate Dance

Hyperphosphatemia is a formidable foe in the fight against CKD. It can lead to a cascade of adverse effects, including bone disorders and cardiovascular disease. This article highlights the critical need for early detection and effective treatment of hyperphosphatemia to prevent these complications. While the authors recognize the importance of traditional approaches, they also emphasize the need for further research and development of novel therapies to address the unique challenges presented by hyperphosphatemia in CKD.

A Journey Towards Improved Renal Health

The fight against CKD is a long and arduous journey, and individuals with this condition face numerous challenges. Hyperphosphatemia is a significant obstacle, but advancements in pharmacotherapy offer hope for better management and improved quality of life. The authors' call for further research is a testament to the ongoing commitment to finding more effective solutions for those battling CKD.

Dr.Camel's Conclusion

Just like a camel traversing a vast desert, individuals with CKD face a demanding journey. Hyperphosphatemia can be a formidable obstacle, but the development of innovative pharmacotherapies provides a glimmer of hope. As researchers continue to explore new avenues, we can expect more effective treatments to help individuals with CKD navigate the complexities of this challenging condition.

Date :
  1. Date Completed 2023-11-02
  2. Date Revised 2023-11-02
Further Info :

Pubmed ID

37527180

DOI: Digital Object Identifier

10.1080/14656566.2023.2243817

SNS
PICO Info
in preparation
Languages

English

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