Combined measles-mumps-rubella-varicella vaccine and febrile convulsions: the risk considered in the broad context.

Author: BertonOlivia, BonanniPaolo, CasabonaGiacomo, KnufMarkus, SinghTina

Paper Details 
Original Abstract of the Article :
INTRODUCTION: Studies on quadrivalent measles, mumps, rubella, and varicella (MMRV) vaccines have indicated a twofold increased relative risk of febrile convulsion (FC) after the first dose compared to MMR and V administered at the same medical visit (MMR+V). AREAS COVERED: This narrative review co...See full text at original site
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引用元:
https://doi.org/10.1080/14760584.2023.2252065

データ提供:米国国立医学図書館(NLM)

MMRV Vaccine: A Look at the Risk of Febrile Convulsions

The world of [vaccination] is constantly evolving, and [quadrivalent measles, mumps, rubella, and varicella (MMRV) vaccines] represent a significant advancement in protecting children from preventable diseases. This research explores the potential risk of [febrile convulsion (FC)] following the first dose of MMRV vaccine, comparing its safety profile to that of [MMR and V administered at the same medical visit (MMR+V)]. The study reviewed previous research on the topic, aiming to provide a [clinical perspective] on the issue of FC occurrence after MMRV vaccination. The authors present a [comprehensive analysis] of the available data, concluding that while MMRV is associated with a [slightly higher] relative risk of FC compared to MMR+V, the [attributable risk] is low. This research highlights the need for a balanced approach, recognizing the benefits of vaccination while acknowledging potential risks and strategies for mitigation.

Understanding the Risks and Benefits of MMRV

This review offers valuable insights into the risk-benefit profile of MMRV, demonstrating that the increased risk of FC is a [minor concern] compared to the significant benefits of vaccination. The study emphasizes that the [low attributable risk] of FC after MMRV should be weighed against the [substantial protection] it provides against serious diseases such as measles, mumps, rubella, and varicella. The authors highlight the importance of addressing parental concerns and ensuring that informed decisions are made regarding vaccination.

Navigating the Desert of Vaccination: Finding Balance in a Complex World

The research on MMRV vaccination reminds us that the world of medicine is full of complex issues, just like a vast desert with its shifting sands and unexpected challenges. We must navigate this landscape with both caution and optimism, acknowledging the potential risks while recognizing the immense benefits of vaccination. The authors encourage a balanced approach, recognizing that the benefits of MMRV outweigh the potential risks, and that informed decision-making is key to navigating this complex issue.

Dr. Camel's Conclusion

This review on MMRV vaccines provides valuable insights into the risks and benefits of vaccination, highlighting the importance of informed decision-making and the need for a balanced perspective. The study reminds us that vaccination is a powerful tool for protecting our children from preventable diseases, and that even with potential risks, the benefits far outweigh the concerns.

Date :
  1. Date Completed 2023-11-02
  2. Date Revised 2023-11-03
Further Info :

Pubmed ID

37642012

DOI: Digital Object Identifier

10.1080/14760584.2023.2252065

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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