Paper Details

  1. Home
  2. Paper Details

Cefadroxil compared with cefaclor in the treatment of streptococcal pneumonia in adults.

Author: CatchpoleM, GentryL, KoornhofH, LoweP, ZeLuffB

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Cefadroxil and cefaclor were effective in treating pneumococcal pneumonia in gold miners. Both antibiotics demonstrated high efficacy and good tolerance, suggesting their potential for treating respiratory tract infections.
Paper Details　
Original Abstract of the Article :
103 young male Black African gold-miners with pneumococcal pneumonia confirmed by culture or serology were randomly assigned to receive the long acting oral cephalosporin cefadroxil 1 g every 12 hours or cefaclor 500 mg every 8 hours for 10 days. Clinical cures were obtained in 94% of the group who ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.2165/00003495-198600323-00008

データ提供：米国国立医学図書館（NLM）

Cefadroxil vs. Cefaclor: A Head-to-Head Comparison in Pneumococcal Pneumonia

Pneumococcal pneumonia, a common and potentially serious respiratory infection, can be effectively treated with antibiotics. This study compares the effectiveness of two oral cephalosporins, cefadroxil and cefaclor, in treating pneumococcal pneumonia in adults. The researchers randomly assigned 103 gold miners with pneumococcal pneumonia to receive either cefadroxil or cefaclor for 10 days. Their findings show that both drugs were equally effective in achieving clinical cures and eradicating the causative organism. This research provides valuable insights into the comparative effectiveness of these two commonly used antibiotics for pneumococcal pneumonia.

Guiding Treatment Decisions: Understanding Comparative Effectiveness

The study's findings highlight the comparative effectiveness of cefadroxil and cefaclor in treating pneumococcal pneumonia. The researchers' data demonstrate that both drugs are equally effective in achieving clinical cures and eradicating the causative organism. This research provides valuable information to guide treatment decisions for individuals with pneumococcal pneumonia.

Combating Bacterial Infections: A Continuous Pursuit

Antibiotic resistance is a growing concern, and researchers are constantly working to develop new and effective therapies to combat bacterial infections. This study highlights the importance of understanding the comparative effectiveness of different antibiotics to ensure that patients receive the most appropriate treatment. By embracing a multi-pronged approach to antibiotic development and utilization, we can work towards a future where bacterial infections are effectively managed and antibiotic resistance is minimized.

Dr.Camel's Conclusion

Just as a camel navigates the vast desert, seeking the most suitable route for its journey, treating bacterial infections requires careful consideration of the most effective antibiotic options. This research provides valuable insights into the comparative effectiveness of cefadroxil and cefaclor, offering guidance for choosing the most appropriate treatment for pneumococcal pneumonia.

Date :
  1. Date Completed 1987-03-17
  2. Date Revised 2018-10-25
Further Info :

Pubmed ID

3803252

DOI: Digital Object Identifier

10.2165/00003495-198600323-00008

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.