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Comparison of acebutolol and propranolol in essential hypertension.

Author: SinghB N, TurlapatyP, WahlJ

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Acebutolol is as effective as propranolol in treating mild to moderately severe essential hypertension but is better tolerated, inducing less heart rate reduction and fewer central nervous system side effects.
Paper Details　
Original Abstract of the Article :
A multicenter, double-blind study compared oral acebutolol (n = 186) with propranolol (n = 190) in the treatment of mild to moderately severe essential hypertension (diastolic greater than or equal to 95 to 129 mm Hg). Both beta blockers produced significant and comparable reductions in diastolic, s...See full text at original site
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引用元：
https://doi.org/10.1016/0002-8703(85)90600-3

データ提供：米国国立医学図書館（NLM）

Acebutolol vs. Propranolol: A Tale of Two Beta Blockers

Essential hypertension, a common condition characterized by high blood pressure, requires careful management. This study compares the effectiveness and tolerability of two beta blockers, acebutolol and propranolol, in treating essential hypertension.

Navigating the Desert of Beta Blocker Therapy

This study reveals that both acebutolol and propranolol effectively reduce blood pressure, demonstrating similar antihypertensive efficacy. However, acebutolol was associated with significantly fewer central nervous system side effects and a smaller reduction in heart rate compared to propranolol. This study highlights the importance of considering individual patient characteristics and potential side effects when selecting beta blocker therapy. This study reminds us that even in the seemingly simple desert of beta blocker therapy, different medications offer distinct profiles, requiring careful consideration for optimal patient care.

Choosing the Right Beta Blocker: A Personalized Approach

This study underscores the need for personalized treatment approaches for essential hypertension, considering the unique characteristics of each patient. The findings suggest that acebutolol may be a preferred option for patients concerned about central nervous system side effects or heart rate reduction. This research encourages a thoughtful and individualized approach to managing hypertension, acknowledging that the desert of therapeutic options is vast and diverse, with a variety of choices available for each patient.

Dr.Camel's Conclusion

This study provides valuable insights into the comparative effectiveness and tolerability of acebutolol and propranolol in treating essential hypertension. The study highlights the importance of considering individual patient characteristics and potential side effects when selecting beta blocker therapy, emphasizing the need for a personalized approach to managing hypertension. This research underscores the importance of careful medication selection, recognizing that the desert of therapeutic options is vast and diverse, with a variety of choices available for each patient.

Date :
  1. Date Completed 1985-02-21
  2. Date Revised 2019-06-26
Further Info :

Pubmed ID

3880995

DOI: Digital Object Identifier

10.1016/0002-8703(85)90600-3

SNS
PICO Info
in preparation
Languages

English

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