[The effects of acebutolol on endocrine and metabolic reactions induced by acute hypoglycaemia. Study in normal subjects and in insulin-dependent diabetics (author's transl)].

Author: AssanR, BentzF, CanivetJ, GauvilleC, PassaP

Paper Details 
Original Abstract of the Article :
Six normal subjects and six normotensive insulin-dependent diabetics underwent two insulin hypoglycaemia tests after administration for three days of either a placebo or of acebutolol--a cardioselective beta-blocker--at a dose of 400 mg per day. The order in which the tests were performed was decide...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/394144

データ提供:米国国立医学図書館(NLM)

The Effects of Acebutolol on Hypoglycemia

Diabetes, like a desert mirage, can be deceiving, requiring careful management to avoid the pitfalls of hypoglycemia. This study investigates the effects of acebutolol, a cardioselective beta-blocker, on endocrine and metabolic responses to acute hypoglycemia in both normal subjects and insulin-dependent diabetics. The study, conducted with a meticulousness as precise as a desert navigator charting a course, aimed to assess the impact of acebutolol on the body's response to low blood sugar.

Acebutolol’s Impact on Hypoglycemic Symptoms

The study found that acebutolol suppressed the tachycardia associated with hypoglycemia, but did not interfere with other warning signs, suggesting that it could potentially be a safe alternative to non-cardioselective beta-blockers in diabetic patients. This finding is like discovering a new species of desert plant that can withstand harsh conditions, offering a potential solution to a medical challenge.

Potential Benefits for Diabetic Patients

The study's findings suggest that acebutolol could be a valuable treatment option for diabetic patients with coronary insufficiency or hypertension, providing a safer alternative to non-cardioselective beta-blockers. This knowledge is like finding a hidden oasis in the desert, providing a potential solution for a challenging medical condition.

Dr. Camel’s Conclusion

This research offers valuable insights into the effects of beta-blockers on hypoglycemia. The study highlights the potential benefits of acebutolol for diabetic patients, providing a promising alternative to traditional beta-blocker therapies. This knowledge is like a desert explorer discovering a new route through a treacherous landscape, paving the way for improved treatment strategies for diabetic patients.

Date :
  1. Date Completed 1980-04-17
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

394144

DOI: Digital Object Identifier

394144

SNS
PICO Info
in preparation
Languages

French

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