A comparative study of dexchlorpheniramine maleate sustained release tablets and budesonide nasal spray in seasonal allergic rhinitis.

Author: MunchE P, MygindN, NørresletT T, SøborgM

Paper Details 
Original Abstract of the Article :
It was the aim of the study to compare the efficacy and side effects of oral antihistamine and nasal glucocorticoid therapy in seasonal allergic, rhinitis. In a double blind, double-dummy, group-comparative study, 61 adult grass pollen allergic patients were either treated with dexchlorpheniramine m...See full text at original site
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引用元:
https://doi.org/10.1111/j.1398-9995.1983.tb02361.x

データ提供:米国国立医学図書館(NLM)

Comparing Treatments for Seasonal Allergies: Oral Antihistamines vs. Nasal Sprays

Seasonal allergies, also known as hay fever, are a common problem that can significantly impact quality of life. This study compared the effectiveness of two different treatments for seasonal allergies: oral antihistamines and nasal glucocorticoid sprays. Think of it like comparing two different ways to navigate a sandstorm: one approach involves wearing a protective mask, while the other involves taking shelter in a cave.

The researchers found that patients using the nasal glucocorticoid spray (budesonide) experienced significantly less nasal blockage than those using the oral antihistamine (dexchlorpheniramine). This means that the nasal spray was more effective at reducing congestion. However, both treatments had a similar impact on sneezing and nose blowing. This is like finding that the protective mask is better at filtering out dust and sand, but both the mask and the cave provide similar protection from the wind.

Nasal Sprays for Better Nasal Relief

The study found that the nasal glucocorticoid spray was more effective at reducing nasal blockage than the oral antihistamine. This suggests that nasal sprays might be a better option for patients experiencing nasal congestion. The study also found that patients using the nasal spray required more eye drops, suggesting that the nasal spray might be more effective at relieving eye symptoms. This could be due to the fact that the nasal spray is applied directly to the nasal passages, while the oral antihistamine has to be absorbed into the bloodstream before it can reach the nose and eyes. Think of it like applying a cooling mist directly to your face to combat the heat of the desert sun, versus taking a pill that might not have the same immediate effect.

Managing Seasonal Allergies

This research suggests that nasal glucocorticoid sprays might be a better option for patients experiencing nasal congestion from seasonal allergies. If you suffer from seasonal allergies, talk to your doctor about the best treatment options for you. They can help you find the best approach, whether it's a mask to filter out the allergens or a cave to escape the storm.

Dr. Camel's Conclusion

This research shows that nasal glucocorticoid sprays can be more effective at reducing nasal blockage than oral antihistamines. Think of it like comparing two different ways to navigate a sandstorm: one approach involves wearing a protective mask, while the other involves taking shelter in a cave. It's important to choose the right treatment for your specific needs and talk to your doctor to find the best solution for your seasonal allergies.

Date :
  1. Date Completed 1983-12-21
  2. Date Revised 2019-08-21
Further Info :

Pubmed ID

6139040

DOI: Digital Object Identifier

10.1111/j.1398-9995.1983.tb02361.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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