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[Results of a comparative therapeutic trial of single-dose treatment of non-complicated acute male gonorrhea].

Author: AncelleR, DolivoM, DurosoirJ L, HewittJ, Martin-BouyerG, ThabautA, TorgalJ, WeinmannJ M

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

A study of 636 patients with gonorrhea compared the effectiveness of four different treatments: spectinomycin, ampicillin plus probenecid, thiamphenicol, and minocycline. All four treatments were equally effective, with cure rates of 96% or higher. While all treatments were associated with some side effects, thiamphenicol caused diarrhea in 28% of patients, minocycline caused dizziness in 13%, and spectinomycin caused pain at the injection site in 18%. Based on effectiveness, side effects, and cost, the study recommends a specific treatment (not specified) for gonorrhea.
Paper Details　
Original Abstract of the Article :
A single dose treatment trial with: spectinomycine 2 g, ampicilline + probenecide 3.5 g + 1 g, thiamphenicol 2.5 g, minocycline 300 mg was undertaken. Three teams were involved, epidemiologists clinicians, microbiologists, 636 patients were included, 483 resumed for control. A negative culture on th...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6225984

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Gonorrhea Treatment

As a researcher, I've encountered many challenges, like navigating a vast and unforgiving desert, in my quest for medical knowledge. This study, like a well-equipped caravan, explores the effectiveness of various single-dose treatments for non-complicated acute male gonorrhea. The researchers meticulously tested four different antibiotics: spectinomycine, ampicilline + probenecide, thiamphenicol, and minocycline. They discovered that, while all the antibiotics demonstrated effectiveness in treating gonorrhea, there were slight variations in their efficacy and side effects. This research, like a map leading to a hidden oasis, offers valuable insights for clinicians seeking the most effective treatment for their patients.

The Importance of Understanding Treatment Options and Side Effects

The study highlights the importance of considering both treatment efficacy and side effects when choosing a therapy for non-complicated acute male gonorrhea. This research, like a well-worn path through the desert, provides crucial information to guide clinicians towards the best therapeutic choices for their patients. The findings suggest that, while all four antibiotics were effective, some were associated with different side effects. This nuanced understanding is crucial for making informed treatment decisions.

Seeking the Best Treatment for Gonorrhea: A Desert Oasis of Knowledge

This research, like a refreshing oasis in the heart of the desert, provides invaluable guidance for clinicians treating non-complicated acute male gonorrhea. The study's meticulous analysis of different treatment options and side effects serves as a compass, guiding clinicians towards the most effective and patient-friendly therapies.

Dr.Camel's Conclusion

This study provides a comprehensive exploration of different treatment options for non-complicated acute male gonorrhea. The researchers, like skilled desert guides, have navigated the complex landscape of treatment efficacy and side effects, offering valuable insights for clinicians. This research, like a well-stocked oasis, provides resources and knowledge to guide clinicians in making informed decisions about the best course of treatment for their patients.
Date :
  1. Date Completed 1983-11-23
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6225984

DOI: Digital Object Identifier

6225984

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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