Decreasing lithium dosage reduces morbidity and side-effects during prophylaxis.

Author: Abou-SalehM, BaileyJ, CoppenA, MillnP, WoodK

Paper Details 
Original Abstract of the Article :
In a prospective double-blind trial we examined the affective morbidity and side-effects of 72 patients who were randomly allocated either to continue with their usual dose of lithium or to receive either a 25% or 50% reduction in lithium dosage. Patients who underwent a dosage reduction with conseq...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/0165-0327(83)90026-5

データ提供:米国国立医学図書館(NLM)

Lithium's Balancing Act: Finding the Right Dose for Mood Disorders

The world of mental health is a vast and complex desert, where researchers are constantly searching for effective treatments for a wide range of conditions. This study focuses on lithium, a medication commonly used to treat bipolar disorder. The researchers, like explorers traversing a desert, are investigating the effects of different lithium dosages on affective morbidity and side effects. Their goal is to find the optimal dosage, like finding a cool oasis in the heat of the desert.

A Dose of Lithium, a Dose of Hope

The study revealed that reducing lithium dosage, while still maintaining therapeutic levels, led to a significant decrease in affective morbidity and side effects. The researchers found that patients who received a 25% or 50% reduction in their lithium dosage experienced fewer mood episodes and experienced fewer side effects. This finding is like discovering a hidden spring in the desert, providing a more comfortable and manageable way to treat mood disorders.

Finding the Right Balance for Optimal Wellbeing

This study emphasizes the importance of finding the right dosage of lithium for each individual patient. It's like finding the perfect balance between the sun and the shade in the desert, where too much or too little can be detrimental. This research highlights the need for personalized treatment approaches and for careful monitoring to ensure optimal outcomes.

Dr. Camel's Conclusion

This study, like a wise old camel guiding a traveler through the desert, emphasizes the need for a nuanced approach to lithium treatment. It highlights the importance of finding the right balance for each individual, ensuring that patients receive the optimal dosage for their specific needs.

Date :
  1. Date Completed 1984-02-28
  2. Date Revised 2019-09-04
Further Info :

Pubmed ID

6229567

DOI: Digital Object Identifier

10.1016/0165-0327(83)90026-5

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.