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Genital herpes - the disease and its treatment including intravenous acyclovir.

Author: MindelA, SutherlandS

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This paper reviews the natural history of genital herpes, previous treatment options, and a double-blind placebo-controlled trial of intravenous acyclovir for severe first-episode genital herpes. Intravenous acyclovir was effective in reducing symptoms and duration of lesions, but did not prevent subsequent recurrences.
Paper Details　
Original Abstract of the Article :
This paper firstly reviews the natural history of genital herpes, giving special attention to the differences between primary and non-primary initial disease and recurrent disease and between herpes simplex virus 1 and 2. Secondly, previous therapies for genital herpes, and in particular the problem...See full text at original site
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引用元：
https://doi.org/10.1093/jac/12.suppl_b.51

データ提供：米国国立医学図書館（NLM）

Intravenous Acyclovir for Severe Genital Herpes

Navigating the complexities of viral infections is akin to traversing a treacherous desert landscape. This research focuses on the treatment of genital herpes, a common and often challenging condition. The study investigates the efficacy of intravenous acyclovir in patients experiencing a severe first attack of genital herpes. The researchers utilized a double-blind placebo-controlled randomized trial, carefully comparing the effects of intravenous acyclovir to a placebo.

The Impact of Intravenous Acyclovir on Genital Herpes Symptoms

The findings reveal that intravenous acyclovir significantly reduced the duration of viral shedding, healing time, and the severity of symptoms in patients with severe first attack genital herpes. However, it did not prevent subsequent recurrences.

The Significance of Intravenous Acyclovir in Managing Genital Herpes

This research highlights the potential of intravenous acyclovir as a valuable tool in managing the symptoms of severe first attack genital herpes. While it doesn't prevent recurrences, it significantly reduces the duration and severity of the initial outbreak, offering much-needed relief to patients. It's like finding an oasis in the middle of a scorching desert - providing respite and support during a challenging time.

Dr.Camel's Conclusion

Like a wise old camel navigating the treacherous desert, this research sheds light on the effectiveness of intravenous acyclovir in managing the symptoms of severe first attack genital herpes. The results demonstrate a clear benefit in reducing viral shedding and symptom duration, offering hope and comfort to patients facing this challenging condition. While it may not completely conquer the disease, intravenous acyclovir serves as a valuable tool in the ongoing journey to manage genital herpes.

Date :
  1. Date Completed 1983-12-20
  2. Date Revised 2019-05-11
Further Info :

Pubmed ID

6355051

DOI: Digital Object Identifier

10.1093/jac/12.suppl_b.51

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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