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[Acute effects of oral acebutolol on exercise tolerance in patients with stable angina pectoris (author's transl)].

Author: BosciaF, De NicolòM, De TomaL, ManginiS, QuagliaraD, RizzonP, ScrutinioD

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Acebutolol significantly improved angina threshold in 12 patients with stable effort angina. Exercise tolerance increased, and heart rate and double product decreased both at rest and during exercise. No significant change in systolic blood pressure was observed.
Paper Details　
Original Abstract of the Article :
Twelve patients affected by stable effort angina were included in a double blind, cross-over study of Acebutolol and Placebo; Acebutolol was orally administered in a dose of 200 mg. Each treatment was preceded by a basal exercise test and, after 120 min a second test was performed to evaluate the ef...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/7026336

データ提供：米国国立医学図書館（NLM）

Acebutolol's Effects on Exercise Tolerance in Stable Angina: A Double-Blind Study

The field of [cardiology] is always searching for innovative ways to manage [stable angina pectoris]. This study used [a double-blind, cross-over study] to assess [the effects of acebutolol on exercise tolerance in patients with stable angina]. The researchers discovered that [acebutolol significantly improved angina threshold and increased the amount of exercise necessary to induce ST segment depression]. This study adds to the growing body of evidence supporting the use of acebutolol in managing stable angina, providing valuable insights for clinicians and researchers alike. The most notable finding is [the significant reduction in heart rate and double product both at rest and at maximal work performed].

Improving Exercise Tolerance in Angina Patients: A Step Forward

The results of this study show [a significant improvement in exercise tolerance] in patients with stable angina. This finding is encouraging as it suggests that [acebutolol can potentially improve the quality of life for patients with stable angina]. It also emphasizes the importance of considering [individualized treatment strategies] based on each patient's unique needs and response to medication.

Living with Angina: Finding Ways to Stay Active

This study reminds us of the importance of finding ways to maintain a healthy lifestyle, even when living with a chronic condition like angina. It provides hope that [medical advancements and effective treatments] can help individuals improve their exercise tolerance and overall quality of life. Dr. Camel advises anyone with angina to consult with their doctor to determine the best treatment options and ways to manage their condition effectively.

Dr.Camel's Conclusion

This study demonstrates the potential benefits of acebutolol in improving exercise tolerance and managing stable angina pectoris. The findings offer encouraging evidence for clinicians and researchers as they continue to explore innovative ways to enhance the quality of life for patients with angina. As Dr. Camel, I encourage individuals with angina to consult with their healthcare provider to discuss personalized treatment strategies and maintain a healthy lifestyle.

Date :
  1. Date Completed 1981-12-19
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7026336

DOI: Digital Object Identifier

7026336

SNS
PICO Info
in preparation
Languages

Italian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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