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Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin's lymphoma.

Author: BronD, CahnJ Y, GisselbrechtC, GuglielmiC, HagenbeekA, HarousseauJ L, PhilipT, SomersR, SonneveldP, Van der LelieH

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

High-dose chemotherapy and autologous bone marrow transplantation increased event-free and overall survival in patients with chemotherapy-sensitive non-Hodgkin's lymphoma in relapse.
Paper Details　
Original Abstract of the Article :
BACKGROUND: High-dose chemotherapy followed by autologous bone marrow transplantation is a therapeutic option for patients with chemotherapy-sensitive non-Hodgkin's lymphoma who have relapses. In this report we describe a prospective randomized study of such treatment. METHOD: A total of 215 patien...See full text at original site
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引用元：
https://doi.org/10.1056/NEJM199512073332305

データ提供：米国国立医学図書館（NLM）

Autologous Bone Marrow Transplantation as Compared With Salvage Chemotherapy in Relapses of Chemotherapy-Sensitive Non-Hodgkin's Lymphoma

Non-Hodgkin's lymphoma, a type of cancer affecting the lymphatic system, can be a daunting challenge for patients. This study, like a research expedition into the complexities of cancer treatment, investigates the effectiveness of high-dose chemotherapy followed by autologous bone marrow transplantation compared to conventional chemotherapy in patients with chemotherapy-sensitive non-Hodgkin's lymphoma experiencing relapses. The study found that autologous bone marrow transplantation significantly improved event-free and overall survival compared to conventional chemotherapy. This research, like a beacon of hope in the desert of cancer, offers valuable insights into the potential benefits of this treatment modality for patients facing lymphoma relapse.

The Promise of Autologous Bone Marrow Transplantation in Lymphoma Treatment

This study provides compelling evidence for the effectiveness of autologous bone marrow transplantation in treating relapses of chemotherapy-sensitive non-Hodgkin's lymphoma. The findings suggest that this treatment modality can significantly improve event-free and overall survival compared to conventional chemotherapy. This is akin to a desert traveler discovering a new oasis, offering a lifeline and hope for a brighter future. This research offers a valuable tool for clinicians treating patients with lymphoma relapse, enabling them to offer more effective and potentially life-saving treatment options.

Embracing Innovation in Cancer Treatment: A Journey of Hope

This study highlights the importance of embracing innovation in cancer treatment. The findings demonstrate that autologous bone marrow transplantation can significantly improve survival rates for patients with lymphoma relapse. This is like a desert traveler discovering a new and more efficient route, offering a faster and safer path to their destination. This research encourages continued exploration of new and innovative treatment approaches, leading to a more hopeful future for cancer patients worldwide.

Dr. Camel's Conclusion

This prospective randomized study compared autologous bone marrow transplantation with salvage chemotherapy in patients with relapses of chemotherapy-sensitive non-Hodgkin's lymphoma. The results demonstrate that autologous bone marrow transplantation significantly improves event-free and overall survival. This research underscores the importance of embracing innovation in cancer treatment, offering a beacon of hope for patients facing lymphoma relapse.
Date :
  1. Date Completed 1995-12-07
  2. Date Revised 2023-10-25
Further Info :

Pubmed ID

7477169

DOI: Digital Object Identifier

10.1056/NEJM199512073332305

SNS
PICO Info
in preparation
Languages

English

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