The antipruritic effects of chlorpheniramine, cyproheptadine and sulphapyridine monitored with limb activity meters on chloroquine induced pruritus among patients with malaria.

Author: OsifoN G

Paper Details 
Original Abstract of the Article :
Limb activity meters, otherwise modified self-winding watches that can record limb agitative movements such as in itch-provoked scratch, were introduced for an objective evaluation of the relative effectiveness of three antipruritic drugs: chlorpheniramine, cyproheptadine, and sulphapyridine for pal...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/7495203

データ提供:米国国立医学図書館(NLM)

Anti-Pruritus Medications: Alleviating the Itch of Chloroquine-Induced Pruritus

As a researcher who has spent countless hours studying the intricate workings of the body, I know that even the smallest sensations, like the itch of a mosquito bite, can be incredibly frustrating. This study explores the use of anti-pruritic medications in alleviating the itch associated with chloroquine-induced pruritus, a side effect of the antimalarial drug chloroquine.

Sulphapyridine: A Potential Solution for Chloroquine-Induced Itch

The study evaluated the efficacy of three anti-pruritic medications: chlorpheniramine, cyproheptadine, and sulphapyridine. Using limb activity meters to objectively measure scratching activity, the researchers found that sulphapyridine significantly reduced upper limb activity in patients experiencing chloroquine-induced pruritus, suggesting its potential as an effective treatment for this distressing condition.

Health Implications and Practical Applications

For individuals experiencing chloroquine-induced pruritus, this study offers a potential solution in the form of sulphapyridine. However, it's crucial to consult with a healthcare professional to determine the most appropriate treatment option and to ensure safe and effective management of this side effect.

Dr. Camel's Conclusion

This study underscores the importance of addressing even seemingly minor side effects of medications. By exploring the efficacy of different anti-pruritic options, the researchers offer valuable insights for managing this distressing condition. It's a reminder that attentiveness to detail and the pursuit of effective solutions are crucial in healthcare, just as a camel navigates the desert with precision and vigilance.

Date :
  1. Date Completed 1996-01-11
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7495203

DOI: Digital Object Identifier

7495203

SNS
PICO Info
in preparation
Languages

English

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