Perindopril plus nifedipine versus perindopril plus hydrochlorothiazide in mild to severe hypertension: a double-blind multicentre study. The Multicentre Study Group on Treatment Association with Perindopril.

Author: AgnesE, DescheP, LetellierP, OverlackA

Paper Details 
Original Abstract of the Article :
Thiazide diuretics are considered as the choice drug to combine with ACE inhibitors for the treatment of hypertension. However, there is much evidence showing that the combination of ACE inhibitors with a calcium channel blocker is effective and safe. We compared the safety and efficacy of perindopr...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8207741

データ提供:米国国立医学図書館(NLM)

A Tale of Two Combinations: Perindopril Plus Nifedipine vs. Perindopril Plus Hydrochlorothiazide

High blood pressure, a silent and insidious condition, can be like a slow-burning desert sandstorm, gradually eroding health over time. This research explores the effectiveness of two different drug combinations in managing hypertension, perindopril plus nifedipine versus perindopril plus hydrochlorothiazide, seeking to identify the most effective approach to combating this pervasive condition.

A Quest for the Optimal Treatment: Comparing Drug Combinations

The study compares the efficacy and safety of two commonly used drug combinations for hypertension, perindopril plus nifedipine and perindopril plus hydrochlorothiazide. This research, like a caravan exploring different paths through a vast desert, seeks to find the most effective route to managing hypertension. The study's findings suggest that both combinations are effective in reducing blood pressure, but further research is needed to definitively determine which approach is superior, a quest akin to finding the most reliable oasis in a challenging landscape.

Navigating the Desert of Hypertension: Finding the Right Treatment

The research highlights the importance of finding the right treatment approach for managing hypertension, a condition that can have a significant impact on overall health. By understanding the nuances of different drug combinations, healthcare providers can make informed decisions, guiding their patients on the most effective path towards managing this prevalent condition. This research, like a map through a complex and sometimes treacherous desert, provides valuable insights into the diverse treatment options available for hypertension, allowing for a more personalized and effective approach to managing this chronic condition.

Dr.Camel's Conclusion

This research compares the efficacy and safety of two commonly used drug combinations for hypertension: perindopril plus nifedipine and perindopril plus hydrochlorothiazide. While both combinations are effective in reducing blood pressure, further research is needed to definitively determine which approach is superior. This research underscores the importance of finding the right treatment approach for managing hypertension, a condition that can have a significant impact on overall health.

Date :
  1. Date Completed 1994-07-14
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8207741

DOI: Digital Object Identifier

8207741

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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