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Atypical cutaneous changes after topical treatment with nitrogen mustard in patients with mycosis fungoides.

Author: GarciaJ A, KaminoH, RamsayD, ReddyV B

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study reviewed biopsy specimens from 10 patients with mycosis fungoides treated with topical nitrogen mustard. The study found atypical histologic changes in the skin resembling those observed with systemic chemotherapy, suggesting that topical nitrogen mustard can produce similar histologic effects as systemic chemotherapeutic agents.
Paper Details　
Original Abstract of the Article :
Side effects in the treatment of mycosis fungoides with topical nitrogen mustard include allergic contact dermatitis, hyperpigmentation, urticaria, and erythema multiforme-like dermatitis. We reviewed biopsy specimens from 10 patients with mycosis fungoides who were treated with topical nitrogen mus...See full text at original site
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引用元：
https://doi.org/10.1097/00000372-199602000-00003

データ提供：米国国立医学図書館（NLM）

Mycosis Fungoides: A Skin Disease with Unexpected Side Effects

Mycosis fungoides is a type of skin cancer, and topical nitrogen mustard is a medication used to treat it. While nitrogen mustard is effective, it can also have unexpected side effects. This study explores the unusual skin changes that can occur after long-term treatment with topical nitrogen mustard, highlighting the importance of careful monitoring and understanding the potential risks.

Topical Nitrogen Mustard: A Double-Edged Sword

This study reveals that topical nitrogen mustard, while effective in treating mycosis fungoides, can lead to atypical skin changes that mimic the effects of systemic chemotherapy. It's important for doctors and patients to be aware of these potential side effects and to closely monitor the skin for any changes.

Skin Health: Paying Attention to the Details

This study emphasizes the importance of careful monitoring for any changes in skin health, especially in patients receiving long-term treatment with topical nitrogen mustard. It's a reminder that even seemingly straightforward treatments can have unforeseen consequences.

Dr.Camel's Conclusion

Like a camel's tough hide, our skin is resilient, but it can be affected by even the most well-intended treatments. This study reminds us that understanding the potential side effects of medications, no matter how effective they may be, is crucial for maintaining good health.

Date :
  1. Date Completed 1996-12-26
  2. Date Revised 2019-09-05
Further Info :

Pubmed ID

8721586

DOI: Digital Object Identifier

10.1097/00000372-199602000-00003

SNS
PICO Info
in preparation
Languages

English

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