Salmeterol versus theophylline in the treatment of asthma.

Author: CoxF M, EmmettA, PollardS J, SpectorS L, YanceyS W

Paper Details 
Original Abstract of the Article :
BACKGROUND: Although theophylline is recommended by current guidelines for the management of asthma in patients with persistent symptoms, theophylline has a narrow therapeutic index, requiring individual dose titration and regular monitoring of serum theophylline concentrations to avoid adverse effe...See full text at original site
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引用元:
https://doi.org/10.1016/S1081-1206(10)63232-2

データ提供:米国国立医学図書館(NLM)

Salmeterol: A New Oasis in the Desert of Asthma Treatment

Asthma, a chronic respiratory condition, can be a real challenge for many people. This study focuses on finding a more effective and tolerable treatment for asthma, comparing the inhalable long-acting bronchodilator, salmeterol, with the oral bronchodilator, theophylline. The research, conducted in two multicenter, randomized, double-blind studies, involved 484 adult and adolescent patients with moderate asthma. Patients were randomly assigned to receive either salmeterol, theophylline, or a placebo for 12 weeks. The study evaluated the effectiveness of each treatment by measuring lung function, asthma symptoms, and overall satisfaction with medication. The results revealed that salmeterol significantly outperformed theophylline and placebo in improving lung function, reducing asthma symptoms, and increasing patient satisfaction. Salmeterol was also associated with fewer gastrointestinal side effects compared to theophylline.

Salmeterol: A Breath of Fresh Air for Asthma Sufferers

This research highlights the potential benefits of salmeterol for asthma management. The findings suggest that salmeterol offers a more effective and tolerable treatment option for patients with moderate asthma compared to theophylline. The study's results are significant because they offer a potential solution for patients struggling with the side effects or ineffectiveness of other asthma medications.

Breathing Easier: Managing Asthma Effectively

Managing asthma effectively requires a multifaceted approach that includes medication, lifestyle modifications, and environmental control. This study provides valuable evidence for the use of salmeterol as a potentially more effective and well-tolerated treatment option for asthma. Working with your doctor to develop a personalized asthma management plan is crucial for achieving optimal control and improving your quality of life.

Dr. Camel's Conclusion

Like a cool breeze in the desert, salmeterol emerges as a promising new treatment for asthma. Its effectiveness in improving lung function, reducing symptoms, and enhancing patient satisfaction makes it a valuable addition to the asthma treatment landscape. This research underscores the importance of exploring new and innovative treatment options to address the diverse needs of patients living with chronic respiratory conditions.
Date :
  1. Date Completed 1997-06-11
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

9164358

DOI: Digital Object Identifier

10.1016/S1081-1206(10)63232-2

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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