[The dose-dependent effects of oral premedication with midazolam].

Author: AlonE, BiroP, BruggerP, PietzschS, WeidmannG

Paper Details 
Original Abstract of the Article :
OBJECTIVE: The aim of this study was to examine the psychological effects, well-being and side effects after various doses of oral midazolam medication. METHODS: After informed consent has been obtained and following the approval by the institutional ethical committee, 80 adult patients in the ASA ...See full text at original site
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引用元:
https://doi.org/10.1055/s-2007-995134

データ提供:米国国立医学図書館(NLM)

The Effects of Oral Midazolam Premedication: A Journey Through the Desert of Anxiolysis

The realm of anesthesia is a vast and complex desert, with patients often experiencing anxiety before medical procedures. This study explores the effects of oral midazolam premedication on anxiety, sedation, and amnesia in patients undergoing various surgical procedures. The researchers administered different doses of midazolam or a placebo to patients and assessed their psychological effects, well-being, and side effects. The findings suggest that midazolam, in a dose-dependent manner, induced anterograde amnesia for visual stimuli, while not significantly affecting anxiolysis compared to placebo. The researchers also found that a dose of 7.5 mg midazolam provided an optimal balance between desirable and undesirable effects.

Midazolam's Anxiolytic Effects: A Desert Oasis with Subtle Shadows

This study highlights the complex effects of midazolam, demonstrating a dose-dependent influence on amnesia but limited anxiolytic effects. The research provides valuable insights into the nuances of midazolam's actions and the need for personalized approaches to premedication.

Navigating the Anesthesia Desert: Personalized Approaches to Premedication

This study underscores the importance of personalized approaches to premedication. While midazolam may offer benefits, its effects can vary significantly depending on the individual and the dose. Understanding these nuances is crucial for optimizing patient care and minimizing potential side effects.

Dr. Camel's Conclusion

The anesthesia desert can be a daunting place, filled with anxieties and uncertainties. Midazolam, like a shimmering oasis, can offer temporary respite, but it's essential to navigate its effects with care, considering individual responses and potential side effects.

Date :
  1. Date Completed 1998-03-12
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

9498887

DOI: Digital Object Identifier

10.1055/s-2007-995134

SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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