Clonidine does not potentiate the antipsychotic effects of neuroleptics in chronically ill patients.

Author: BigelowL B, El-MallakhR S, ElkashefA, HedgesS, IssaF, WyattR J

Paper Details 
Original Abstract of the Article :
Clonidine is a centrally acting antihypertensive and has been prescribed widely for more than 20 years. Because it decreases central norepinephrine activity, clonidine has been investigated as an antipsychotic. In most of the preliminary studies, clonidine was tested as the sole antipsychotic agent....See full text at original site
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引用元:
https://doi.org/10.1023/a:1026194411452

データ提供:米国国立医学図書館(NLM)

Clonidine does not potentiate the antipsychotic effects of neuroleptics in chronically ill patients

Mental illness, like a desert mirage, can be deceptive and challenging to navigate. This study, published in 1998, explores the potential benefits of combining clonidine, a medication used to manage blood pressure, with neuroleptics, drugs used to treat psychosis. The researchers wanted to investigate whether adding clonidine to neuroleptic therapy could enhance the antipsychotic effects and improve outcomes for patients with chronic mental illness.

Finding the Right Approach - A Journey of Personalized Care

The study found that combining clonidine with neuroleptics did not result in a significant improvement in antipsychotic effects compared to using neuroleptics alone. It's like realizing that different desert plants thrive under different conditions, requiring a tailored approach to care. This suggests that while clonidine may have some benefits for managing certain symptoms, it may not be a suitable addition to neuroleptic treatment for all patients.

Managing Mental Illness - A Complex and Evolving Landscape

This research underscores the importance of carefully considering individual patient needs and tailoring treatment approaches to maximize benefits and minimize risks. It's a reminder that, just as a camel must adapt to the changing landscape of the desert, we need to remain open to new approaches and adapt treatment strategies as our understanding of mental illness evolves.

Dr.Camel's Conclusion

This research highlights the complexity of managing mental illness and the importance of finding personalized and effective treatment approaches for each individual. It's a journey of understanding, just like a camel's trek across the vast desert, leading us to a deeper appreciation of the human mind and the challenges of mental health.

Date :
  1. Date Completed 1998-08-28
  2. Date Revised 2019-11-02
Further Info :

Pubmed ID

9622044

DOI: Digital Object Identifier

10.1023/a:1026194411452

SNS
PICO Info
in preparation
Languages

English

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