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Haemodynamic and renal effects of felodipine in young and elderly subjects.

Author: AbergJ, JohanssonP, LandahlS, LernfeltB, SeligmanL

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Felodipine had similar effects on central and renal hemodynamics in both young and elderly subjects. While the drug lowered blood pressure and vascular resistance in both groups, the effects were more pronounced in elderly individuals. However, there was no effect on glomerular filtration rate.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To study the influence of age on renal and haemodynamic effects of the calcium antagonist felodipine. METHODS: Eight young (mean age 27 years) and eight elderly (mean age 75 years) healthy normotensive subjects were given felodipine intravenously for 120 min aiming at close to therapeuti...See full text at original site
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引用元：
https://doi.org/10.1007/s002280050520

データ提供：米国国立医学図書館（NLM）

Felodipine: A Journey Through Age and Blood Pressure

Cardiovascular health is a critical aspect of well-being, as important as a steady supply of water in a desert. This study examines the effects of felodipine, a medication used to treat high blood pressure, on young and elderly individuals.

Researchers administered felodipine intravenously to both groups and monitored their blood pressure, renal function, and other cardiovascular parameters. The results demonstrated that felodipine effectively lowered blood pressure in both young and elderly individuals, with no significant differences in its effects. Importantly, the study also found that felodipine did not negatively impact renal function in either group.

Felodipine: A Bridge Across Generations

The study's findings suggest that felodipine can be an effective treatment option for hypertension across a wide age range, providing valuable insights into the medication's safety and efficacy. This is crucial for managing cardiovascular health effectively, particularly in an aging population.

Maintaining Cardiovascular Oasis: A Journey Through Life

Maintaining cardiovascular health is essential throughout life. Adopting a heart-healthy lifestyle, including regular exercise, a balanced diet, and managing stress, is crucial. Consulting with a healthcare professional is essential to determine the most appropriate treatment options and monitor your cardiovascular health.

Dr.Camel's Conclusion

Felodipine appears to be a reliable oasis in the desert of hypertension, offering effective blood pressure control for both young and elderly individuals. Understanding the impact of medications on the body, coupled with a healthy lifestyle, is key to maintaining cardiovascular well-being throughout life.

Date :
  1. Date Completed 1999-03-26
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

9860145

DOI: Digital Object Identifier

10.1007/s002280050520

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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