Maintenance of remission of ulcerative colitis: a comparison between balsalazide 3 g daily and mesalazine 1.2 g daily over 12 months. ABACUS Investigator group.

Author: CroweJ P, GibsonJ A, GreenJ R, HoldsworthC D, KerrG D, LoboA J, SchofieldK J, SwarbrickE T, TaylorM D

Paper Details 
Original Abstract of the Article :
BACKGROUND: Despite widespread use of aminosalicylates as maintenance treatment for ulcerative colitis (UC), patients still report troublesome symptoms, often nocturnally. AIM: To compare the efficacy and safety of balsalazide (Colazide) with mesalazine (Asacol) in maintaining UC remission. METHOD...See full text at original site
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引用元:
https://doi.org/10.1046/j.1365-2036.1998.00427.x

データ提供:米国国立医学図書館(NLM)

Maintaining Ulcerative Colitis Remission: Balsalazide vs Mesalazine

Ulcerative colitis, a chronic inflammatory bowel disease, is a relentless desert wind that can wreak havoc on the digestive system. This study investigates the effectiveness of two medications, balsalazide and mesalazine, in maintaining remission of ulcerative colitis. The researchers compare the efficacy and safety of these drugs over a 12-month period to determine the best option for patients seeking to manage their condition.

Balsalazide: A Potential Oasis in the Desert of Ulcerative Colitis

The results of this study suggest that balsalazide may be a more effective treatment option for maintaining remission of ulcerative colitis, especially during the initial three months of treatment. The authors found that balsalazide patients experienced fewer relapses, more symptom-free nights, and better control of nocturnal symptoms compared to patients receiving mesalazine. This finding offers a glimmer of hope in the desert of ulcerative colitis research, providing potential for improved management and quality of life for patients.

Navigating the Complex Terrain of Ulcerative Colitis Management

This study underscores the importance of considering individual patient needs when choosing a treatment pathway for ulcerative colitis. Just as a desert traveler needs to be aware of the changing landscapes, clinicians must be mindful of the nuances of different medications and their potential effects on patients. The research emphasizes the need for ongoing research to better understand the long-term efficacy and safety of these drugs, providing patients with the best possible care and maximizing their chances of achieving and maintaining remission.

Dr. Camel's Conclusion

This research is a beacon in the desert of ulcerative colitis management, offering a potentially more effective treatment option in balsalazide. The study highlights the importance of individualizing treatment, carefully considering patient factors and medication characteristics to optimize outcomes. As we continue to explore the vast landscape of inflammatory bowel disease, the results of this study will undoubtedly serve as a guidepost, helping to improve the lives of patients battling this chronic and challenging condition.

Date :
  1. Date Completed 1999-04-21
  2. Date Revised 2019-08-31
Further Info :

Pubmed ID

9882028

DOI: Digital Object Identifier

10.1046/j.1365-2036.1998.00427.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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