著者: TanabeNobuhiro, FukudaKeiichi, MatsubaraHiromi, NakanishiNorifumi, TaharaNobuhiro, IkedaSatoshi, KishiTakuya, SatohToru, HirataKen-Ichi, InoueTeruo, KimuraHiroshi, OkanoYoshiaki, OkazakiOsamu, SataMasataka, TsujinoIchizo, UenoShuichi, YamadaNorikazu, YaoAtsushi, KuriyamaTakayuki

原題: Selexipag for Chronic Thromboembolic Pulmonary Hypertension in Japanese Patients　- A Double-Blind, Randomized, Placebo-Controlled, Multicenter Phase II Study.

著者: KloseHans, ChinKelly M, EwertRalf, GallHenning, ParambilJoseph, PochDavid, SeyfarthHans-Jürgen, AxelsenLene N, Hsu SchmitzShu-Fang, SteinClaudia, PrestonIoana R

原題: Temporarily switching from oral to intravenous selexipag in patients with pulmonary arterial hypertension: safety, tolerability, and pharmacokinetic results from an open-label, phase III study.

著者: AkagiSatoshi, DohiYoshihiro, IshikawaKaori, KubotaKayoko, HorimotoKoshin, YagiShusuke, HirataTetsuo, YamamotoEiichiro, ItoHiroshi, NakamuraKazufumi

原題: Effects of Dual Initial Combination Therapy With Macitentan Plus Riociguat or Macitentan Plus Selexipag on Hemodynamics in Patients With Pulmonary Arterial Hypertension (SETOUCHI-PH Study)　- Protocol of a Multicenter Randomized Control Trial.

著者: PatelNiti M, StottlemyerBritney A, GrayMatthew P, BoyceRichard D, Kane-GillSandra L

原題: A Pharmacovigilance Study of Adverse Drug Reactions Reported for Cardiovascular Disease Medications Approved Between 2012 and 2017 in the United States Food and Drug Administration Adverse Event Reporting System (FAERS) Database.

著者: KrauseA, MachacekM, LottD, HurstN, BrudererS, DingemanseJ

原題: Population Modeling of Selexipag Pharmacokinetics and Clinical Response Parameters in Patients With Pulmonary Arterial Hypertension.

著者: ChinKelly M, RubinLewis J, ChannickRichard, Di ScalaLilla, GaineSean, GalièNazzareno, GhofraniHossein-Ardeschir, HoeperMarius M, LangIrene M, McLaughlinVallerie V, PreissRalph, SimonneauGérald, SitbonOlivier, TapsonVictor F

原題: Association of N-Terminal Pro Brain Natriuretic Peptide and Long-Term Outcome in Patients With Pulmonary Arterial Hypertension.

著者: GaineSean, ChinKelly, CoghlanGerry, ChannickRichard, Di ScalaLilla, GalièNazzareno, GhofraniHossein-Ardeschir, LangIrene M, McLaughlinVallerie, PreissRalph, RubinLewis J, SimonneauGérald, SitbonOlivier, TapsonVictor F, HoeperMarius M

原題: Selexipag for the treatment of connective tissue disease-associated pulmonary arterial hypertension.

著者: AxelsenLene Nygaard, PoggesiItalo, RasschaertFreya, Perez RuixoJuan Jose, BrudererShirin

原題: Clopidogrel, a CYP2C8 inhibitor, causes a clinically relevant increase in the systemic exposure to the active metabolite of selexipag in healthy subjects.

著者: MorrisonKeith, StuderRolf, ErnstRoland, HaagFranck, KauserKatalin, ClozelMartine

原題: Differential effects of Selexipag [corrected] and prostacyclin analogs in rat pulmonary artery.

著者: ArevaloCarlo, WhiteR James, LachantDaniel

原題: Transitioning selexipag to oral treprostinil in patients with pulmonary artery hypertension.

著者: SitbonOlivier, ChinKelly M, ChannickRichard N, BenzaRaymond L, Di ScalaLilla, GaineSean, GhofraniHossein-Ardeschir, LangIrene M, McLaughlinVallerie V, PreissRalph, RubinLewis J, SimonneauGérald, TapsonVictor F, GalièNazzareno, HoeperMarius M

原題: Risk assessment in pulmonary arterial hypertension: Insights from the GRIPHON study.

著者: BoehlerMargaux, BrudererShirin, UlčIvan, DingemanseJasper

原題: Biocomparison Study of Adult and Paediatric Dose Strengths of the Prostacyclin Receptor Agonist Selexipag.

著者: NoelZachary R, KidoKazuhiko, MacaulayTracy E

原題: Selexipag for the treatment of pulmonary arterial hypertension.

著者: CorbozMichel R, PlauntAdam J, MalininVladimir S, LiZhili, GauaniHelena, ChunDonald, CipollaDavid, PerkinsWalter R, ChapmanRichard W

原題: Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension.

著者: ChenHongliu, ShenYing, LiangYi, QiuYing, XuMeili, LiChaoqian

原題: Selexipag Improves Lipopolysaccharide-Induced ARDS on C57BL/6 Mice by Modulating the cAMP/PKA and cAMP/Epac1 Signaling Pathways.

著者: ZhaoJie, WangMei, YuQing, YangYi, ZhangBin, ZhanSanhua

原題: A real-world analysis of safety profile of selexipag by using FDA adverse Event Reporting System (FAERS).

著者: KuwanoKeiichi, KosugiKeiji, FuchikamiChiaki, FunakiShunji

原題: [Pharmacological characteristics and clinical study results of Selexipag (Uptravi^® tablets), a selective prostacyclin receptor agonist].

著者: PatelJigisha A, ShenLei, HallSusan M, BenyahiaChabha, NorelXavier, McAnultyRobin J, MoledinaShahin, SilversteinAdam M, WhittleBrendan J, ClappLucie H

原題: Prostanoid EP₂ Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells.

著者: LuoQin, JinQi, ZhaoZhihui, ZhaoQing, YuXue, YanLu, ZhangYi, XiongChangming, LiuZhihong

原題: Targeted therapy in pulmonary veno-occlusive disease: time for a rethink?

著者: MorrisonKeith, HaagFranck, ErnstRoland, IglarzMarc, ClozelMartine

原題: Selective Prostacyclin Receptor Agonist Selexipag, in Contrast to Prostacyclin Analogs, Does Not Evoke Paradoxical Vasoconstriction of the Rat Femoral Artery.

著者: MenonAravind A, SahaySandeep, BravermanLewis E, FarberHarrison W

原題: Thyroid Dysfunction in Patients with Pulmonary Artery Hypertension (PAH): The Effect of Therapies Affecting the Prostanoid Pathway.

著者: GatfieldJohn, MenyhartKatalin, WannerDaniel, GnerreCarmela, MonnierLucile, MorrisonKeith, HessPatrick, IglarzMarc, ClozelMartine, NaylerOliver

原題: Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low <i>&#946;</i>-Arrestin Recruitment and Desensitization Potential.

著者: BrudererShirin, Petersen-SyllaMarc, BoehlerMargaux, RemeňováTatiana, HalabiAtef, DingemanseJasper

原題: Effect of gemfibrozil and rifampicin on the pharmacokinetics of selexipag and its active metabolite in healthy subjects.

著者: LemmersJacqueline Mj, FretheimHåvard, KnaapenHanneke Ka, van den HoogenFrank Hj, van Haren-WillemsJolanda Hgm, DuijnhouwerAnthony L, van DijkArie P, van den EndeCornelia Hm, Hoffmann-VoldAnna-Maria, VonkMadelon C

原題: Selexipag treatment in patients with systemic sclerosis-associated pulmonary arterial hypertension in clinical practice, a case series.