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Nebivolol versus nifedipine in the treatment of essential hypertension: a double-blind, randomized, comparative trial.
Author: DupontA G, KorliparaK, LacourcièreY, MarcadetD M, RobertsonJ I, Van NuetenL, VyssoulisG
Original Abstract of the Article :
The efficacy and acceptability of 5 mg nebivolol once daily, a long-acting, vasodilating cardioselective beta blocker that additionally facilitates the L-arginine/nitric oxide system, was assessed in a double-blind, randomized trial in comparison with 20 mg nifedipine retard twice daily in patients ...See full text at original site
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引用元:
https://doi.org/10.1097/00045391-199807000-00006
データ提供:米国国立医学図書館(NLM)
Nebivolol vs. Nifedipine: A Battle in the Desert of Hypertension
Hypertension, a condition where blood pressure is consistently elevated, can be a silent threat to health. It's like a sandstorm that gradually erodes the body's systems. This study compares the effectiveness and tolerability of two medications, nebivolol and nifedipine, in treating essential hypertension.
The researchers, like skilled desert warriors, conducted a double-blind, randomized trial involving patients with essential hypertension. They compared the effects of nebivolol, a beta-blocker that also facilitates the L-arginine/nitric oxide system, to nifedipine, a calcium channel blocker. They monitored blood pressure, heart rate, and side effects over time.
Nebivolol: A Powerful Weapon Against Hypertension
The researchers found that nebivolol, like a powerful weapon in the desert, was more effective than nifedipine at reducing blood pressure in the first two weeks of treatment. Both drugs effectively lowered blood pressure in the long term, but nebivolol was better tolerated and had a more consistent effect throughout the day.
Choosing the Right Weapon: Tailoring Treatment for Hypertension
This study, like a guide through the desert of hypertension, highlights the importance of choosing the right medication for each individual patient. It emphasizes the need for personalized approaches to treatment and the importance of considering both efficacy and tolerability when selecting medications for hypertension.
Dr. Camel's Conclusion
This study, like a camel caravan navigating a challenging terrain, reminds us that there is no one-size-fits-all approach to treating hypertension. Nebivolol emerged as a potentially effective and well-tolerated option, but further research is needed to confirm its long-term benefits. It's a reminder that the journey towards better health requires careful consideration of individual needs and the exploration of new and innovative treatment strategies.
Date :
- Date Completed 2000-02-23
- Date Revised 2019-11-03
Further Info :
English
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