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Effects of prophylactic nalmefene on the incidence of morphine-related side effects in patients receiving intravenous patient-controlled analgesia.

Author: ChehadeJ, DuffyL, GajrajN, JohnsonE R, JoshiG P, WesevichJ

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study was designed to determine the dose-response relation for nalmefene for the prevention of morphine-related side effects in patients receiving intravenous patient-controlled analgesia.
Paper Details　
Original Abstract of the Article :
Opioid-related side effects associated with intravenous patient-controlled analgesia can be reduced by a low-dose naloxone infusion. The influence of nalmefene, a pure opioid antagonist with a longer duration of action, on opioid-related side effects has not been evaluated. This study was designed t...See full text at original site
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引用元：
https://doi.org/10.1097/00000542-199904000-00013

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 1999-04-21
  2. Date Revised 2019-06-28
Further Info :

Pubmed ID

10201671

DOI: Digital Object Identifier

10.1097/00000542-199904000-00013

SNS
PICO Info
in preparation
Languages

English

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