Paper Details

  1. Home
  2. Paper Details

Laboratory measures of methylphenidate effects in cocaine-dependent patients receiving treatment.

Author: CresonD L, GrabowskiJ, RhoadesH M, RoacheJ D, SchmitzJ M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study examined the effects of methylphenidate in patients with cocaine dependence.
Paper Details　
Original Abstract of the Article :
Two experiments examined the effects of methylphenidate in male and female patients enrolled in an outpatient treatment program for primary cocaine dependence. The first study was a component of a double-blind efficacy trial wherein 57 patients were first tested in a human laboratory for their initi...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1097/00004714-200002000-00011

データ提供：米国国立医学図書館（NLM）

Methylphenidate's Effects on Cocaine-Dependent Patients: A Camel's Perspective

The world of [Addiction Research] is vast and complex, like the endless dunes of the Sahara. This study dives deep into the effects of methylphenidate, a stimulant medication, on patients struggling with cocaine dependence. They used a [double-blind efficacy trial] to examine the impact of methylphenidate on [heart rate, subjective ratings, and cocaine craving] in a group of 57 patients. Think of it like exploring a hidden oasis in the desert – researchers meticulously studied the effects of this medication on their participants, seeking to understand its potential for helping those struggling with addiction.

Methylphenidate: A Potential Oasis in the Desert of Addiction?

The results showed that methylphenidate increased heart rate and some negative subjective feelings, like anxiety and depression, but it did not increase cocaine craving. This suggests that while it might not be the perfect solution, it could potentially offer a new pathway for treatment. Like a caravan searching for a water source, researchers are finding promising leads in the quest for effective treatments for cocaine dependence.

The Importance of Understanding Individual Responses

One of the most interesting insights from this study is that individual responses to methylphenidate varied significantly. Just as each dune in the desert has its own unique shape, so too does each person respond differently to medication. This emphasizes the importance of personalized treatment approaches, taking into account the specific needs and characteristics of each individual.

Dr. Camel's Conclusion

This study is a valuable step forward in understanding the potential role of stimulant medications in the treatment of cocaine dependence. While methylphenidate may not be a miracle cure, it offers a glimmer of hope in the ongoing battle against addiction. Like a camel finding a hidden spring in the desert, researchers are uncovering new possibilities for helping those who are struggling.

Date :
  1. Date Completed 2000-03-15
  2. Date Revised 2019-09-10
Further Info :

Pubmed ID

10653210

DOI: Digital Object Identifier

10.1097/00004714-200002000-00011

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.