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International study comparing cefdinir and cefuroxime axetil in the treatment of patients with acute exacerbation of chronic bronchitis.

Author: KeyserlingC H, LanganC E, NemethM A, RudolphC, SiemonG, TackK J, Van HerwaardenC L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The efficacy and tolerability of cefdinir, once or twice daily, and cefuroxime were comparable with no significant differences between the regimens used.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: To assess the efficacy and tolerability of three antibiotic regimens in patients with acute exacerbation of chronic bronchitis. METHODS: In this double-blind, randomized, multicentered, parallel-group study, patients received once-daily cefdinir 600 mg, twice-daily cefdinir 300 mg, or t...See full text at original site
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引用元：
https://doi.org/10.1016/s1201-9712(00)90062-6

データ提供：米国国立医学図書館（NLM）

Acute Exacerbation of Chronic Bronchitis: Comparing Antibiotic Treatments

Chronic bronchitis is a common respiratory condition that can lead to recurring flare-ups, known as acute exacerbations. Choosing the right antibiotic treatment for these exacerbations is crucial for managing symptoms and preventing complications. This double-blind, randomized, multicentered study, published in [Journal Name], compared the efficacy and tolerability of three antibiotic regimens in patients with acute exacerbation of chronic bronchitis.

Ceftinir Shows Comparable Efficacy and Tolerability to Cefuroxime

The study found that cefdinir, administered once or twice daily, demonstrated comparable efficacy and tolerability to cefuroxime axetil in treating acute exacerbations of chronic bronchitis. This finding suggests that cefdinir may be a viable alternative treatment option for patients with this condition. The authors highlight the importance of considering individual patient factors, such as the severity of symptoms and potential drug interactions, when selecting an antibiotic.

Navigating the Desert of Respiratory Infections: Choosing the Right Treatment

Think of the respiratory system as a labyrinthine network of airways, constantly exposed to the elements. Chronic bronchitis is like a sandstorm that irritates and inflames these airways, leading to recurring exacerbations. This study provides a valuable guide for navigating the desert of respiratory infections, comparing different treatment options and emphasizing the importance of personalized care.

Dr.Camel's Conclusion

This research adds valuable information to the field of chronic bronchitis management, highlighting the comparable effectiveness of cefdinir and cefuroxime axetil in treating acute exacerbations. It's a reminder that in the vast desert of respiratory illnesses, we have multiple tools and resources available to manage these conditions effectively, providing comfort and relief to those affected.

Date :
  1. Date Completed 2000-03-23
  2. Date Revised 2019-11-03
Further Info :

Pubmed ID

10689211

DOI: Digital Object Identifier

10.1016/s1201-9712(00)90062-6

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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