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Efficacy and safety of tianeptine in the treatment of depressive disorders in comparison with fluoxetine.

Author: AnsseauM, Costa e Silva JACE, DillingH, HerringtonR, LôoH, Saiz-RuizJ, Vaz-SerraA, de RisioS

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Both tianeptine and fluoxetine showed good efficacy and safety in treating depression.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Depression is treated by a great variety of antidepressant treatments. SSRIs (such as fluoxetine) are well known: it is, however, sure that further progress is needed and the search for antidepressants with other mechanisms of action (such as tianeptine) or different efficacy is still of...See full text at original site
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引用元：
https://doi.org/10.1016/s0165-0327(99)00009-9

データ提供：米国国立医学図書館（NLM）

Efficacy and Safety of Tianeptine in the Treatment of Depressive Disorders

The world of [depression] is a complex and challenging one, like a vast and often treacherous desert. This study, like a skilled physician offering new treatment options, explores the efficacy and safety of [tianeptine] in comparison to [fluoxetine] for the treatment of [depressive disorders]. The researchers sought to determine if tianeptine, an antidepressant with a different mechanism of action, could provide comparable efficacy and safety to fluoxetine, a commonly prescribed SSRI.

Tianeptine: A Promising Option for Depression Treatment

The study found that [tianeptine and fluoxetine] exhibited comparable efficacy in reducing depressive symptoms. This finding is like discovering a new oasis in the desert of depression treatment, offering a potential alternative for patients who may not respond well to SSRIs. The researchers also noted that both drugs had [similar safety profiles], suggesting that tianeptine could be a viable option for a wider range of patients.

Expanding Treatment Options for Depression

The study highlights the importance of [expanding treatment options] for depression, taking into account the unique needs and preferences of individual patients. It's like offering a desert traveler a variety of paths to their destination, ensuring they can choose the route that best suits their needs and abilities. By understanding the diversity of depression and its treatment, we can better address the needs of those who are suffering and promote their overall well-being.

Dr.Camel's Conclusion

This study offers encouraging evidence for the efficacy and safety of tianeptine as a treatment for depressive disorders. It's like finding a new oasis in the desert of mental health, providing a promising alternative for those who may not respond well to traditional treatments. By expanding our understanding of depression and its treatment, we can offer hope and support to those who are struggling and create a brighter future for mental health.

Date :
  1. Date Completed 2000-03-24
  2. Date Revised 2019-09-05
Further Info :

Pubmed ID

10701468

DOI: Digital Object Identifier

10.1016/s0165-0327(99)00009-9

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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