Paper Details 
Original Abstract of the Article :
OBJECTIVES: To evaluate adherence, side effects and efficacy of a modality of highly active antiretroviral therapy (HAART) in HIV-infected patients. METHODS: In a cohort, prospective study, 65 previously treated patients received stavudine plus lamivudine plus nelfinavir. Fifty-three participants (...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/10942640

データ提供:米国国立医学図書館(NLM)

Adherence to Antiretroviral Therapy: A Critical Factor in HIV Treatment

This study delves into the challenges of adherence to highly active antiretroviral therapy (HAART) among treatment-experienced HIV-infected patients. Imagine a desert oasis, where a deadly virus threatens its inhabitants. HAART, like a powerful antidote, is crucial for combating the virus, but its effectiveness depends on consistent use.

The study found that adherence to a specific HAART regimen, stavudine plus lamivudine plus nelfinavir, was poor, with only 46% of patients achieving adequate adherence. This is like a struggling desert oasis, where the antidote is not being distributed consistently, weakening its ability to protect the inhabitants. The study highlights the importance of factors such as female sex and low baseline HIV RNA levels in influencing adherence, suggesting that these factors can play a role in the effectiveness of treatment. This is akin to identifying key factors that contribute to the success of the antidote's distribution, ensuring its effectiveness in protecting the oasis.

The Importance of Adherence in HIV Treatment

This study underscores the importance of adherence to HAART in achieving successful HIV treatment outcomes. The findings emphasize the need for comprehensive support and counseling to help patients maintain consistent adherence to their medication regimens, improving their chances of a healthy and fulfilling life. This is like building a reliable and efficient system for distributing the antidote to the desert oasis, maximizing its impact and protecting its inhabitants.

Navigating the Challenges of HIV

This research highlights the ongoing challenges associated with HIV treatment, particularly the complexities of adherence. It emphasizes the need for ongoing research and development of new and more effective treatment strategies, as well as interventions to improve adherence, allowing us to combat this virus more effectively and create a brighter future for those affected. Just as a skilled desert explorer must overcome obstacles and adapt to the changing landscape, we must continue to explore and innovate to combat the challenges posed by HIV.

Dr.Camel's Conclusion

This study serves as a stark reminder of the importance of patient adherence in HIV treatment. It highlights the need for continued research to develop more effective and easier-to-adhere-to therapies, as well as comprehensive support programs to ensure successful outcomes for those living with HIV. Like a wise desert guide, we must constantly strive to improve our understanding and approaches to this complex and challenging disease.

Date :
  1. Date Completed 2000-10-13
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

10942640

DOI: Digital Object Identifier

S0163-4453(00)90678-9

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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