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[Effects of calcium antagonists on atherosclerosis progression and intima media thickness].

Author: ZannadF

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Calcium antagonists are a first-choice treatment for hypertension and angina. While some short-acting calcium antagonists may increase mortality, long-acting calcium antagonists, such as amlodipine, may have protective effects against atherosclerosis. Amlodipine was found to stabilize carotid intima media thickness, suggesting that it may be beneficial in preventing ischaemic events.
Paper Details　
Original Abstract of the Article :
Calcium antagonists are currently considered first-choice agents for treating hypertension. They are also active antianginal drugs. Their protective effects against ischaemia and their antiatherogenic potential, which have been demonstrated in various experimental models, may contribute to their pre...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/11002857

データ提供：米国国立医学図書館（NLM）

Calcium Antagonists: A Complex Landscape in Atherosclerosis

Atherosclerosis, like a slow-moving sandstorm, can silently erode the health of our arteries. This research delves into the complex effects of calcium antagonists, a class of medications commonly used for hypertension and angina, on atherosclerosis progression. The researchers, like cartographers mapping a vast desert, analyzed a range of studies exploring the impact of calcium antagonists on various measures of atherosclerosis, including intima media thickness (IMT).

The researchers found that while some studies showed promising results with calcium antagonists, others revealed inconsistent or even detrimental effects. This suggests that the effects of calcium antagonists on atherosclerosis are complex and dependent on factors such as the specific drug, dosage, and duration of treatment.

Calcium Antagonists: A Tale of Two Deserts

This research paints a complex picture of the effects of calcium antagonists on atherosclerosis. It's like navigating two distinct deserts - one where calcium antagonists may offer protection, and another where their effects are less clear.

Calcium Antagonists: A Cautious Approach is Key

This research emphasizes the importance of personalized medicine and careful monitoring when using calcium antagonists for atherosclerosis. Just as a camel caravan requires careful planning and vigilance to navigate a desert, physicians should consider the specific needs of each patient when prescribing calcium antagonists.

Dr.Camel's Conclusion

This research explores the complex relationship between calcium antagonists and atherosclerosis, highlighting the need for further research to fully understand their effects on cardiovascular health. It's like navigating a vast and often unpredictable desert, where a cautious approach and personalized care are crucial.

Date :
  1. Date Completed 2001-01-18
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

11002857

DOI: Digital Object Identifier

11002857

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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