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A controlled study of nortriptyline in children and adolescents with attention deficit hyperactivity disorder.

Author: BiedermanJ, BosticJ Q, MillsteinR, PolisnerD A, PrinceJ B, SpencerT J, WilensT E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Nortriptyline (NT) effectively reduces symptoms of ADHD and oppositionality in children and adolescents. In a study of 35 patients, NT significantly reduced ADHD and oppositional symptoms. Robust dosing was well tolerated with minimal adverse events.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: To study the efficacy and tolerability of nortriptyline (NT) in the treatment of pediatric attention deficit hyperactivity disorder (ADHD). METHODOLOGY: Subjects were outpatient children and adolescents with ADHD ascertained from clinical referrals. Subjects were enrolled in a 6-week op...See full text at original site
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引用元：
https://doi.org/10.1089/10445460050167304

データ提供：米国国立医学図書館（NLM）

Nortriptyline for ADHD: A Camel's Journey Through the Desert of Attention

Attention deficit hyperactivity disorder (ADHD) is a complex neurodevelopmental disorder, and finding effective treatments is crucial for improving the lives of children and adolescents. This study investigates the efficacy and tolerability of [nortriptyline (NT)] in treating pediatric ADHD. The researchers conducted a [6-week open study followed by a 3-week, double-blind, controlled discontinuation phase] and found that [NT significantly reduced ADHD and oppositional symptoms] in a majority of participants. The study also suggests that [NT was well-tolerated] with minimal adverse events and even led to weight gain in some participants.

A Desert of Distractions: Finding Focus with Nortriptyline

Imagine a camel trying to navigate a desert filled with swirling sandstorms and alluring mirages. This analogy reflects the challenges faced by children with ADHD, who struggle to focus and control their impulses. Nortriptyline, in this scenario, is a guide that helps them find a path through the distractions and reach their destination. The study's findings suggest that nortriptyline can provide a valuable tool for managing ADHD symptoms, enabling children to focus and achieve their full potential.

A Camel's Word of Caution: Navigating the Desert of Medications

As a camel, I understand the importance of choosing the right path in the vast desert of medications. While this study suggests the effectiveness of nortriptyline for ADHD, it's crucial to discuss potential side effects and treatment plans with a healthcare professional. Remember, every child's journey is unique, and finding the right path requires careful consideration and expert guidance.

Dr. Camel's Conclusion

Nortriptyline, a beacon of hope in the desert of ADHD, offers a potential path towards improved focus and reduced symptoms. While further research is needed to fully understand its long-term effects, this study suggests that nortriptyline can be a valuable tool in managing ADHD, helping children navigate the desert of distractions and reach their full potential.

Date :
  1. Date Completed 2001-02-08
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

11052409

DOI: Digital Object Identifier

10.1089/10445460050167304

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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