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Thioridazine for dementia.

Author: HarveyR J, KellyC A, KirchnerV

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Neuroleptic drugs, like thioridazine, are often prescribed for elderly patients with dementia, despite evidence suggesting they may worsen cognitive decline. Thioridazine, known for its sedative effect, may have detrimental anticholinergic effects on cognitive function.
Paper Details　
Original Abstract of the Article :
Neuroleptic drugs are controversial treatments in dementia, with evidence accumulating that they may hasten clinical decline. Despite these concerns, they are commonly prescribed for elderly and demented patients. Thioridazine, a phenothiazine neuroleptic, has been commonly prescribed because it was...See full text at original site
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引用元：
https://doi.org/10.1002/14651858.CD000464

データ提供：米国国立医学図書館（NLM）

Thioridazine for Dementia: A Controversial Treatment

This study delves into the controversial use of thioridazine, a phenothiazine neuroleptic, for dementia. While thioridazine has been prescribed for its sedative effects, its anticholinergic properties raise concerns about its potential detrimental impact on cognitive function. The author cautions that the use of neuroleptics in dementia requires careful consideration, as evidence suggests they may hasten clinical decline. This research underscores the need for more research to determine the true benefits and risks of thioridazine in dementia.

The Dilemma of Treating Dementia with Neuroleptics

The study highlights the complex issues surrounding the use of neuroleptics in dementia. While these drugs may offer temporary relief from behavioral symptoms, their potential to accelerate cognitive decline raises serious concerns. This research emphasizes the need for a balanced approach to dementia treatment, weighing the potential benefits against the potential risks.

Navigating Dementia Treatment Options

When considering treatment options for dementia, it's essential to consult with a healthcare professional and carefully weigh the potential benefits and risks of each approach. This research underscores the importance of continuous research and development of safer and more effective treatment options for dementia. It's also crucial to understand that each individual's needs and responses to treatment may vary.

Dr.Camel's Conclusion

The use of thioridazine in dementia is like a mirage in the desert - it offers a fleeting promise of relief but may ultimately lead to a more challenging journey. This research emphasizes the importance of careful consideration when navigating the complex terrain of dementia treatment, ensuring that the chosen path is safe and beneficial for the patient. Just as a wise camel caravan navigates the desert with caution and foresight, we must approach dementia treatment with the same level of care and understanding.

Date :
  1. Date Completed 2002-03-28
  2. Date Revised 2020-05-11
Further Info :

Pubmed ID

11686961

DOI: Digital Object Identifier

10.1002/14651858.CD000464

SNS
PICO Info
in preparation
Languages

English

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