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The therapeutic ratio of R-albuterol is comparable with that of RS-albuterol in asthmatic patients.

Author: ArvidssonP, LötvallJ, MaloneyA, PalmqvistM, VentrescaG P, WardJ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The R-albuterol/RS-albuterol potency ratios for local (FEV(1)) and systemic effects (heart rate and K(+)) are similar, suggesting a comparable therapeutic ratio for R-albuterol and RS-albuterol in asthmatic subjects.
Paper Details　
Original Abstract of the Article :
BACKGROUND: It has been suggested that R-albuterol produces bronchodilation that is comparable with that of racemic albuterol (RS-albuterol) on a 4:1 dose-for-dose basis but systemic side effects on a 2:1 basis, implying better therapeutic ratio for R-albuterol. OBJECTIVE: We sought to carefully co...See full text at original site
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引用元：
https://doi.org/10.1067/mai.2001.119152

データ提供：米国国立医学図書館（NLM）

R-Albuterol: A Promising Treatment for Asthma

In the world of medicine, a constant pursuit is to find more effective and targeted treatments for various ailments. Asthma, a chronic respiratory condition, is no exception. This research explores the potential of a specific form of albuterol, R-albuterol, as a potential therapeutic option for asthma.

The researchers conducted a study involving asthmatic patients, comparing the effects of R-albuterol, S-albuterol, and racemic albuterol (RS-albuterol) on lung function and systemic effects. They carefully measured changes in lung capacity, heart rate, and potassium levels, providing a comprehensive assessment of the medications' impact.

R-Albuterol: Comparable Therapeutic Effect to Racemic Albuterol

Their findings indicated that R-albuterol, like RS-albuterol, effectively improved lung function in asthmatic patients. The researchers concluded that R-albuterol has a comparable therapeutic ratio to RS-albuterol, meaning it offers similar benefits with comparable side effects.

Asthma Management: A Personalized Approach

This research highlights the importance of considering different treatment options for asthma, emphasizing that a one-size-fits-all approach may not always be the best solution. Individualizing treatment based on a patient's specific needs and characteristics is crucial.

Dr.Camel's Conclusion

Finding the right treatment for asthma is like finding a cool oasis in a hot desert. This research offers a promising alternative, R-albuterol, that could provide relief for asthmatic patients. It reminds us that innovation and exploration are essential in the pursuit of better healthcare options.

Date :
  1. Date Completed 2001-12-21
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

11692096

DOI: Digital Object Identifier

10.1067/mai.2001.119152

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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