The use of alpha-adrenoceptor antagonists in lower urinary tract disease.

Author: Chess-WilliamsRussell

Paper Details 
Original Abstract of the Article :
alpha-adrenoceptor antagonists have traditionally been used in the treatment of hypertension but in recent years they have become increasingly common in the treatment of benign prostatic enlargement (BPE), where they reduce the 'dynamic' component of bladder outlet obstruction and appear to have add...See full text at original site
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引用元:
https://doi.org/10.1517/14656566.3.2.167

データ提供:米国国立医学図書館(NLM)

Alpha-Adrenoceptor Antagonists: A New Frontier in Lower Urinary Tract Disease

The field of [Lower Urinary Tract Disease] is constantly evolving, seeking new and effective treatments for conditions like benign prostatic enlargement (BPE). This research dives deep into the world of alpha-adrenoceptor antagonists, which have traditionally been used to combat hypertension. The authors delve into how these drugs are becoming increasingly popular in treating BPE, as they can reduce bladder outlet obstruction and alleviate irritative symptoms. They go on to discuss the various types of alpha-adrenoceptor antagonists available in the UK, including prazosin, doxazosin, indoramin, terazosin, tamsulosin, and alfuzosin, and their potential side effects. Interestingly, the study highlights the uroselective alpha-adrenoceptor antagonists, tamsulosin and alfuzosin, which are relatively new to the market. These agents exhibit selectivity via different mechanisms, and their cardiovascular side effects are comparable to placebo. The study suggests that these antagonists may work through additional mechanisms, potentially benefitting other bladder conditions.

Promising Prospects for Lower Urinary Tract Disease Treatment

This research presents a compelling case for the potential of alpha-adrenoceptor antagonists as a promising treatment option for various lower urinary tract disorders. The study's findings, particularly regarding the uroselective agents, offer a glimmer of hope for patients suffering from these conditions.

Unlocking New Possibilities in Bladder Health

This study sheds light on the potential of alpha-adrenoceptor antagonists in addressing a range of bladder issues. If future research supports these findings, we may see a shift in the treatment landscape for lower urinary tract disease. This could lead to improved quality of life for millions of individuals affected by these conditions.

Dr. Camel's Conclusion

Imagine a desert oasis, a place of respite and renewal. That's what these alpha-adrenoceptor antagonists could be for those battling lower urinary tract issues. This research opens up a promising avenue for treating these conditions, potentially offering relief and improved quality of life for countless individuals. Like a camel traversing the vast desert, we must continue to explore and investigate these new avenues in search of solutions to these persistent health challenges.

Date :
  1. Date Completed 2002-07-24
  2. Date Revised 2019-09-16
Further Info :

Pubmed ID

11829730

DOI: Digital Object Identifier

10.1517/14656566.3.2.167

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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