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Efficacy and tolerability of low-dose iron supplements during pregnancy: a randomized controlled trial.

Author: CrowtherCaroline A, GibsonRobert A, GibsonRosalind S, MakridesMaria, SkeaffC Murray

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Supplementing pregnant women with 20 mg/d of iron from week 20 of gestation until delivery was effective in preventing iron deficiency anemia and iron deficiency without anemia. This low-dose iron supplementation did not result in significant gastrointestinal side effects.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Iron deficiency anemia (IDA) is common in pregnant women, but previous trials aimed at preventing IDA used high-dose iron supplements that are known to cause gastrointestinal side effects. OBJECTIVE: The objective was to assess the effect on maternal IDA and iron deficiency (ID, without...See full text at original site
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引用元：
https://doi.org/10.1093/ajcn/78.1.145

データ提供：米国国立医学図書館（NLM）

Low-Dose Iron Supplementation During Pregnancy: A Randomized Controlled Trial

Pregnancy is a remarkable journey, but it can also be a time of nutritional challenges. Iron deficiency anemia (IDA) is a common issue during pregnancy, often treated with high-dose iron supplements, which can lead to gastrointestinal side effects. This research explores a more gentle approach, evaluating the effectiveness and tolerability of low-dose iron supplementation (20 mg/d) in pregnant women. The results, obtained from a randomized, double-blind, placebo-controlled trial, show that low-dose iron supplementation was effective in preventing both IDA and iron deficiency (ID) without causing significant gastrointestinal side effects.

Low-Dose Iron Supplementation: A Promising Strategy

This study demonstrates the efficacy of low-dose iron supplementation for preventing IDA and ID in pregnant women. The results, obtained from a large sample of 430 women, show a significant reduction in both IDA and ID in the iron-supplemented group compared to the placebo group. This finding is particularly encouraging given the lack of significant side effects observed in the iron-supplemented group.

A Safer Option for Maternal Health

Low-dose iron supplementation provides a safer alternative to high-dose iron supplements, potentially mitigating gastrointestinal side effects. This is like providing a refreshing oasis of iron to pregnant women, ensuring their well-being and that of their developing babies, without the discomfort of a harsh desert wind (side effects).

Dr.Camel's Conclusion

This study highlights the effectiveness and tolerability of low-dose iron supplementation in pregnant women. The results suggest that low-dose iron supplementation is a safe and effective strategy for preventing IDA and ID, offering a gentler approach to addressing these common pregnancy challenges.

Date :
  1. Date Completed 2003-07-08
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

12816784

DOI: Digital Object Identifier

10.1093/ajcn/78.1.145

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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