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Evaluation of ticarcillin/clavulanic acid versus ceftriaxone plus amikacin for fever and neutropenia in pediatric patients with leukemia and lymphoma.

Author: CyprianoMonica, DantasLenice Silva, LeeLúcia Martino, PetrilliAntonio Sérgio, Pires PereiraCarlos Alberto, Torres B SilvaKatia Veronica, Vercillo LuisiMaria Flávio Augusto

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Ticarcillin/clavulanic acid was found to be as successful as the combination of ceftriaxone plus amikacin in pediatric and adolescent patients with leukemia or lymphoma who presented with fever and neutropenia during chemotherapy.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The empirical use of antibiotic treatments is widely accepted as a means to treat cancer patients in chemotherapy who have fever and neutropenia. Intravenous monotherapy, with broad spectrum antibiotics, of patients with a high risk of complications is a possible alternative. METHODS: W...See full text at original site
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引用元：
https://doi.org/10.1590/s1413-86702003000200003

データ提供：米国国立医学図書館（NLM）

Treating Fever and Neutropenia in Pediatric Cancer Patients: A Comparison of Antibiotics

The world of pediatric oncology is a delicate and challenging landscape, like a desert where every step requires careful consideration. This study explores the effectiveness of different antibiotic regimens for treating fever and neutropenia, a common complication in children with leukemia and lymphoma undergoing chemotherapy. The researchers compared the efficacy of ticarcillin/clavulanic acid versus ceftriaxone plus amikacin in a randomized, open-label study.

Ticarcillin/Clavulanic Acid: A Viable Option for Pediatric Cancer Patients

The study found that ticarcillin/clavulanic acid was as successful as the combination of ceftriaxone plus amikacin in treating fever and neutropenia in pediatric patients with leukemia or lymphoma. This suggests that ticarcillin/clavulanic acid is a viable option for this group of patients, particularly those at high risk for infections.

Navigating Pediatric Cancer Care: A Team Approach

This research highlights the importance of carefully considering treatment options and individual patient factors when managing fever and neutropenia in pediatric cancer patients. It underscores the need for a multidisciplinary approach to care, involving oncologists, infectious disease specialists, and pharmacists. As Dr. Camel, I emphasize the importance of open communication between healthcare providers and parents to ensure the best possible care for their children.

Dr. Camel's Conclusion

This study, like a desert oasis providing relief to weary travelers, sheds light on the effective treatment of fever and neutropenia in pediatric cancer patients. It emphasizes the importance of careful consideration of treatment options and the vital role of multidisciplinary collaboration in providing comprehensive care for these vulnerable individuals. Let us continue to explore and refine treatment strategies, ensuring the best possible outcomes for children with cancer.

Date :
  1. Date Completed 2004-03-11
  2. Date Revised 2019-10-26
Further Info :

Pubmed ID

12959681

DOI: Digital Object Identifier

10.1590/s1413-86702003000200003

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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