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Evaluation of immune complexes after immunotherapy with wheat flour in bakers' asthma.

Author: ArmentiaA, ArranzM, BarberD, BlancoA, MartinJ M, SalcedoG, SanchezP, de la FuenteR

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of 26 patients with baker's asthma investigated the effectiveness and safety of immunotherapy with wheat flour. The study also looked for the presence of circulating immune complexes (CICs) after two years of treatment. The study aims to provide evidence for the use of immunotherapy for inhalant food allergies and to evaluate the potential role of CICs in any adverse reactions.
Paper Details　
Original Abstract of the Article :
Inhalant food allergy has been described many times in literature, but double-blind clinical trials to support successful hyposensitization to these allergens has seldom been reported. Some authors have suspected that certain adverse reactions after immunotherapy may be mediated by immune complexes....See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1456487

データ提供：米国国立医学図書館（NLM）

Bakers' Asthma: Exploring the Desert of Inhalant Food Allergies

This research delves into the challenging realm of bakers' asthma, a condition caused by an allergic reaction to inhaled wheat flour. The authors investigate the efficacy of immunotherapy with wheat flour, a therapeutic approach akin to venturing into the desert of allergen desensitization.

Immunotherapy for Bakers' Asthma: A Journey Through the Desert of Allergies

The authors conducted a double-blind clinical trial to evaluate the effectiveness of immunotherapy in treating bakers' asthma. While they did not find conclusive evidence to support the use of immunotherapy with wheat flour, the study provides valuable insights into the potential mechanisms of action and the need for further research. This research journey is similar to exploring a vast desert landscape, where some paths lead to dead ends, but others may reveal hidden treasures.

Navigating the Desert of Allergies: Seeking Solutions

This research highlights the complexity of treating bakers' asthma, emphasizing the need for continued research and exploration of alternative therapeutic approaches. As Dr. Camel, I believe that understanding the mechanisms of allergen desensitization is crucial to developing effective and safe treatments for this condition, just as understanding the dynamics of desert ecosystems is crucial for navigating its complexities.

Dr. Camel's Conclusion

While this study did not find conclusive evidence supporting the use of immunotherapy with wheat flour for bakers' asthma, it sheds light on the complexities of this condition and the need for further research. This research underscores the ongoing challenges of treating inhalant food allergies and the importance of developing targeted therapeutic approaches.

Date :
  1. Date Completed 1993-01-07
  2. Date Revised 2004-11-17
Further Info :

Pubmed ID

1456487

DOI: Digital Object Identifier

1456487

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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