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Management of opioid side effects in cancer-related and chronic noncancer pain: a systematic review.

Author: , BennettKyle, CarrDaniel, ChewPriscilla W, FiskRuth A, Gialeli-GoudasMaria, Horowicz-MehlerNathalie, LauJoseph, McNicolEwan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review assessed the management of opioid side effects in cancer pain management and chronic noncancer pain. Well-designed trials are needed to provide evidence-based guidelines for managing opioid side effects.
Paper Details　
Original Abstract of the Article :
Side effects can limit opioid dosage and reduce quality of life. The purpose of this systematic review was to assess the management of opioid side effects in the context of cancer pain management or, in the event that no evidence was available for cancer pain, for chronic noncancer pain. The side ef...See full text at original site
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引用元：
https://doi.org/10.1016/s1526-5900(03)00556-x

データ提供：米国国立医学図書館（NLM）

Managing Opioid Side Effects in Cancer and Chronic Noncancer Pain

Opioids are commonly used to manage pain, but they can cause a range of side effects that can limit their effectiveness and impact quality of life. This systematic review examines the evidence for managing opioid side effects in both cancer pain and chronic noncancer pain. The researchers focused on side effects such as constipation, pruritus, nausea and vomiting, myoclonus, sedation, respiratory depression, and delirium. They also explored the use of opioid rotation as a strategy to manage side effects. The review found that evidence for the effectiveness of various interventions for managing opioid side effects varies considerably, highlighting the need for well-designed trials to provide clinicians with clear guidance on best practices.

Navigating the Side Effects of Opioid Therapy

Opioids are a powerful tool for pain management, but their use can be complicated by side effects. This systematic review provides a valuable overview of the evidence for managing these side effects. The findings highlight the need for further research to develop more effective and evidence-based interventions to improve the safety and efficacy of opioid therapy.

Balancing Pain Relief and Side Effects

Managing opioid side effects is essential for ensuring the safety and effectiveness of this important class of medications. This review underscores the importance of careful monitoring and the use of evidence-based strategies to minimize side effects and optimize patient outcomes.

Dr.Camel's Conclusion

This systematic review emphasizes the importance of addressing opioid side effects to improve the safety and efficacy of pain management. The need for well-designed trials is paramount to provide clinicians with robust evidence-based guidance for effectively managing these side effects. As a camel traversing a vast desert, we must continually seek out knowledge and resources that can guide us towards more effective and compassionate pain management strategies.

Date :
  1. Date Completed 2003-12-17
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

14622694

DOI: Digital Object Identifier

10.1016/s1526-5900(03)00556-x

SNS
PICO Info
in preparation
Languages

English

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