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Novel treatment of chronic severe hand dermatitis with bexarotene gel.

Author: BrenemanD, HanifinJ M, ShethP, StevensV

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Clinical Trial, Phase IThe first stage of clinical trials in humans. Evaluates the safety, tolerability, and pharmacokinetics of a new drug/treatment.
Clinical Trial, Phase IIA Phase II trial is a trial that further evaluates the efficacy and safety of a new drug or treatment, whose safety has been confirmed to some extent in a Phase I trial, in a small number of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Topical corticosteroids are effective for milder forms of hand dermatitis, but their effectiveness often diminishes over time and they can cause skin atrophy.
Paper Details　
Original Abstract of the Article :
Hand dermatitis is an eczematous inflammation of the hands that is related to occupation or to routine activities. It often becomes chronic, and in some patients may become severe and disabling. Topical corticosteroids are effective treatment, particularly for milder forms, but they often lose effec...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15030340

データ提供：米国国立医学図書館（NLM）

Bexarotene Gel for Chronic Hand Dermatitis

Chronic hand dermatitis, a persistent skin condition, can significantly affect daily activities and overall well-being. This study investigates the potential of bexarotene gel, a topical retinoid, as a treatment for chronic, severe hand dermatitis. The researchers explore bexarotene gel as an alternative to topical corticosteroids, which can become less effective over time and can lead to skin thinning. The study aims to assess the efficacy and safety of bexarotene gel in managing this challenging skin condition.

A New Approach for Chronic Hand Dermatitis

This study, like a resourceful traveler discovering a new oasis in the desert, explores a novel treatment for chronic hand dermatitis. Bexarotene gel, a topical retinoid, has the potential to provide an alternative to topical corticosteroids, offering a new avenue for managing this persistent skin condition.

Managing Skin Conditions

Chronic skin conditions can be frustrating and persistent. This study highlights the importance of seeking effective treatment options and exploring alternatives when traditional therapies become less effective.

Dr.Camel's Conclusion

Chronic hand dermatitis can be a tough condition to manage, but research is constantly searching for new solutions. This study, like a desert flower blooming amidst harsh conditions, offers hope for those struggling with chronic hand dermatitis. Bexarotene gel's potential to provide a safe and effective alternative to corticosteroids is a significant development in managing this persistent skin condition.

Date :
  1. Date Completed 2004-05-03
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

15030340

DOI: Digital Object Identifier

BJD5729

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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