Inhaled fluticasone versus inhaled beclomethasone or inhaled budesonide for chronic asthma.

Author: AdamsN, BestallJ M, JonesP W, LassersonT J

Paper Details 
Original Abstract of the Article :
BACKGROUND: Beclomethasone dipropionate (BDP) and budesonide (BUD) are commonly prescribed inhaled corticosteroids for the treatment of asthma, Fluticasone propionate (FP) is newer agent with greater potency in in-vitro assays. OBJECTIVES: To compare the efficacy and safety of Fluticasone to Beclom...See full text at original site
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引用元:
https://doi.org/10.1002/14651858.CD002310.pub2

データ提供:米国国立医学図書館(NLM)

Inhaled Corticosteroids for Asthma Treatment

Asthma, a chronic respiratory disease, can create a desert of breathlessness and discomfort for those who suffer from it. This study compares the efficacy and safety of three inhaled corticosteroids, fluticasone, beclomethasone, and budesonide, in the treatment of chronic asthma. The researchers conducted a systematic review of the literature, pooling data from 48 randomized controlled trials.

Comparing Inhaled Corticosteroids for Asthma

The review found that fluticasone, when administered at half the dose of beclomethasone or budesonide, led to small but significant improvements in lung function, as measured by forced expiratory volume in one second (FEV1) and peak expiratory flow (PEF). However, fluticasone was associated with a higher risk of pharyngitis when administered at the same dose as beclomethasone or budesonide.

Navigating the Desert of Asthma

This research provides valuable information for the management of chronic asthma. The review's findings highlight the importance of considering both efficacy and safety when choosing an inhaled corticosteroid for treatment. As we navigate the desert of asthma, we must seek treatments that effectively manage symptoms while minimizing the risk of adverse effects.

Dr.Camel's Conclusion

This study provides a comprehensive overview of the relative efficacy and safety of inhaled corticosteroids for asthma. The findings underscore the importance of individualizing treatment approaches based on patient characteristics and preferences. As we continue to journey through the desert of asthma, we must remain vigilant in our pursuit of effective and safe therapies to improve the lives of those affected by this condition.

Date :
  1. Date Completed 2004-08-17
  2. Date Revised 2020-05-11
Further Info :

Pubmed ID

15106173

DOI: Digital Object Identifier

10.1002/14651858.CD002310.pub2

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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