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Double-blind, randomized, vehicle-controlled clinical trial of once-daily benzoyl peroxide/clindamycin topical gel in the treatment of patients with moderate to severe rosacea.

Author: BrenemanDebra, LevySharon, LeydenJames, SavinRonald, VamvakiasGeorge, VandePolChristine

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Historical ArticleA research paper that analyzes past events and developments using primary sources and examines them from a historical perspective.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Topical application of a combination of 5% benzoyl peroxide and 1% clindamycin was effective and well tolerated in patients with moderate to severe rosacea.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Systemic antibiotics such as tetracycline are well accepted as effective in treating the inflammatory papular/pustular phase of rosacea but may be associated with systemic side-effects. Few controlled data on the use of topical antibiotics in rosacea are available. OBJECTIVE: We evaluat...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15117375

データ提供：米国国立医学図書館（NLM）

Benzoyl Peroxide/Clindamycin: A Topical Solution for Rosacea

This study delves into the world of [rosacea], a chronic inflammatory skin condition that can be as frustrating as a sandstorm on a caravan journey! The researchers are investigating the efficacy of a fixed combination of 5% benzoyl peroxide and 1% clindamycin in a topical gel for treating moderate to severe rosacea. They conducted a double-blind, vehicle-controlled, randomized clinical trial, comparing the effects of the combination gel to a placebo. The study showed that the combination gel significantly reduced papules and pustules, as well as overall rosacea severity, compared to the placebo.

A Topical Remedy for Rosacea

This research is like discovering a refreshing oasis in the desert of rosacea, offering a new and effective topical solution for this stubborn skin condition. The researchers have demonstrated the effectiveness of the benzoyl peroxide/clindamycin combination gel, providing hope for patients seeking relief from the symptoms of rosacea.

Managing Rosacea

Rosacea is a chronic skin condition that requires ongoing management. It's important to consult with a healthcare professional for proper diagnosis and treatment.

Dr.Camel's Conclusion

This study is a valuable contribution to the field of dermatology, offering a new and effective topical treatment for rosacea. The researchers have successfully demonstrated the efficacy of the benzoyl peroxide/clindamycin combination gel, providing a promising option for patients seeking relief from this common skin condition. I encourage everyone to consult with a dermatologist for proper diagnosis and management of rosacea.
Date :
  1. Date Completed 2004-08-19
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15117375

DOI: Digital Object Identifier

IJD2283

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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