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Effect of a treatment strategy of tight control for rheumatoid arthritis (the TICORA study): a single-blind randomised controlled trial.

Author: CapellHilary, GrigorCatriona, KincaidWilma, LockPeter, McMahonAlex D, PorterDuncan, StirlingAnne, VallanceRamsay

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

While medications are used to treat rheumatoid arthritis (RA), many patients don’t respond well. This study aims to determine if a more intensive outpatient program, focusing on closely managing disease activity, is more effective than standard outpatient care.
Paper Details　
Original Abstract of the Article :
Present treatment strategies for rheumatoid arthritis include use of disease-modifying antirheumatic drugs, but a minority of patients achieve a good response. We aimed to test the hypothesis that an improved outcome can be achieved by employing a strategy of intensive outpatient management of patie...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15262104

データ提供：米国国立医学図書館（NLM）

Tight Control Strategy for Rheumatoid Arthritis

Rheumatoid arthritis (RA) can feel like a relentless desert storm, attacking the joints and causing pain and inflammation. This study investigates the effectiveness of a treatment strategy called 'tight control' for RA, aiming to achieve sustained control of disease activity through intensive outpatient management.

A New Strategy for Managing Rheumatoid Arthritis

The researchers compared the outcomes of tight control with routine outpatient care in patients with RA. While the study found no significant difference in outcomes between the two groups, it highlights the importance of personalized treatment approaches and close monitoring to manage RA effectively.

Tailoring Treatment for Individual Needs

This study underscores the importance of tailoring treatment strategies to individual patient needs. While the tight control strategy didn't show a significant benefit in this study, it may be beneficial for certain patients, particularly those with more severe or active disease. It's crucial to consult with a healthcare professional to discuss the best treatment options for RA, as each individual's response to therapy may vary.

Dr.Camel's Conclusion

This study navigates the complex desert of rheumatoid arthritis treatment, exploring the potential of a tight control strategy to manage disease activity. While the study didn't find a clear advantage for this approach, it highlights the importance of individualized care and close monitoring to achieve optimal outcomes for patients with RA.

Date :
  1. Date Completed 2004-07-30
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

15262104

DOI: Digital Object Identifier

S0140673604166762

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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