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Treatment of interictal epileptiform discharges can improve behavior in children with behavioral problems and epilepsy.

Author: BinnieColin D, PresslerRonit M, RobinsonRichard O, WilsonGoigia A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Suppressing interictal discharges can improve behavior in children with epilepsy, particularly partial epilepsy.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: It is generally agreed that children should be treated for epilepsy only if they have clinical seizures. The aim of this study was to examine whether suppressing interictal discharges can affect behavior in children with epilepsy. STUDY DESIGN: In a double-blinded, placebo-controlled, c...See full text at original site
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引用元：
https://doi.org/10.1016/j.jpeds.2004.08.084

データ提供：米国国立医学図書館（NLM）

Suppressing Interictal Epileptiform Discharges: Impact on Behavior

This research investigates the intriguing relationship between [Interictal epileptiform discharges (IEDs)] and [Behavioral problems] in [Children with epilepsy]. The study examines the potential of [Suppressing IEDs] with [Lamotrigine] to [Improve behavior] in [Children with well-controlled or mild epilepsy]. The researchers conducted a [Double-blind, placebo-controlled, crossover study] and found that [Behavioral improvement] was specifically seen in [Patients with a significant reduction in IEDs]. This finding suggests that [Treating IEDs] could be a valuable strategy for [Managing behavioral problems] in [Children with epilepsy].

Targeting IEDs for Behavioral Improvement

The research demonstrates that [Suppressing IEDs] can [Improve behavior] in [Children with epilepsy and behavioral problems]. The study found that [Behavioral improvement] was significantly associated with [Reduced IED frequency or duration], especially in [Patients with partial epilepsy]. This highlights the importance of [Considering IEDs] as a [Potential target] for [Behavioral interventions] in [Children with epilepsy].

Navigating the Labyrinth of Epilepsy

Imagine a labyrinth of [Epilepsy] where [IEDs] can create challenging pathways for both children and their families. This research is like a map, guiding us through the complexities of [Epilepsy] and its impact on [Behavior]. The findings suggest that [Targeting IEDs] could be a valuable strategy for [Improving outcomes] for children with [Epilepsy and behavioral problems]. Just as a camel navigates the desert, we must be persistent in our efforts to find solutions for those affected by this complex condition.

Dr.Camel's Conclusion

This research is like a desert oasis, offering a glimmer of hope for children with [Epilepsy and behavioral problems]. The findings suggest that [Treating IEDs] could be a valuable strategy for improving [Behavioral outcomes]. This research reminds us that even in the challenging landscape of epilepsy, we must continue to search for new solutions and therapies, ensuring that all children with epilepsy have the best possible chance at a fulfilling life.

Date :
  1. Date Completed 2005-03-01
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

15644834

DOI: Digital Object Identifier

10.1016/j.jpeds.2004.08.084

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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