Autologous stem cells derived from the peripheral blood compared to standard bone marrow transplant; time to engraftment: a systematic review.

Author: LewisAlly

Paper Details 
Original Abstract of the Article :
Lymphoma patients who require high dose chemotherapy are 'rescued' by reinfusion of stem cells to repopulate their bone marrow and minimise the risk of fatal infections or haemorrhage. This review evaluated the evidence for the use of stem cells derived from the peripheral blood to speed the engraft...See full text at original site
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引用元:
https://doi.org/10.1016/j.ijnurstu.2005.01.007

データ提供:米国国立医学図書館(NLM)

Stem Cells for Lymphoma: A Race to Repopulate the Bone Marrow

Lymphoma patients undergoing high-dose chemotherapy face a daunting challenge: rebuilding their bone marrow. This study delves into the world of stem cell transplants, examining a crucial question: do stem cells derived from the peripheral blood lead to faster engraftment compared to the traditional bone marrow transplant? The researchers conducted a systematic review of existing studies, comparing the recovery of neutrophils and platelets in patients receiving these two types of transplants.

Faster Recovery with Peripheral Blood Stem Cells: A Promising Trend

The results suggest a clear advantage for peripheral blood stem cell transplantation. All four studies included in the review showed faster neutrophil recovery with peripheral blood stem cells, and three out of four demonstrated the same trend for platelet engraftment. These findings point to a more efficient and potentially quicker road to recovery for lymphoma patients.

Stem Cell Transplantation: A Lifeline for Lymphoma Patients

This research underscores the significance of peripheral blood stem cell transplantation for lymphoma patients. While more research is needed to fully understand its long-term effects and cost-effectiveness, this study offers a beacon of hope for faster recovery and a better chance at regaining strength.

Dr. Camel's Conclusion

This study is a reminder that even in the vast desert of medical research, we're constantly discovering new oases of hope. Peripheral blood stem cell transplantation might just be the key to unlocking a quicker, smoother path to recovery for lymphoma patients. However, like any new discovery, it needs to be explored further to ensure its safety and efficacy.

Date :
  1. Date Completed 2005-08-30
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

15921990

DOI: Digital Object Identifier

10.1016/j.ijnurstu.2005.01.007

SNS
PICO Info
in preparation
Languages

English

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