The British Rheumatoid Outcome Study Group (BROSG) randomised controlled trial to compare the effectiveness and cost-effectiveness of aggressive versus symptomatic therapy in established rheumatoid arthritis.

Author: DaviesL, DawesP, RobertsC, ScottD L, SymmonsD, TrickerK

Paper Details 
Original Abstract of the Article :
OBJECTIVES: To examine the effectiveness and cost-effectiveness of symptomatic versus aggressive treatment in patients with established, stable rheumatoid arthritis (RA). DESIGN: A randomised observer-blinded controlled trial and economic evaluation with an initial assessment at randomisation and f...See full text at original site
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引用元:
https://doi.org/10.3310/hta9340

データ提供:米国国立医学図書館(NLM)

Treating Rheumatoid Arthritis: A Desert of Options

Rheumatoid arthritis (RA), like a relentless desert sandstorm, can cause chronic pain, inflammation, and joint damage. This study compares the effectiveness and cost-effectiveness of two treatment approaches for established RA: aggressive therapy and symptomatic therapy. The authors conduct a randomized controlled trial, akin to testing different strategies for navigating a desert landscape.

Aggressive vs. Symptomatic Therapy: A Desert Oasis of Choice

The study found that aggressive therapy, aimed at suppressing both clinical and laboratory evidence of inflammation, did not significantly improve physical function or other clinical outcomes compared to symptomatic therapy, which focused on symptom control. This is like finding two different oases in the desert, one offering a more intensive and potentially risky approach to survival, while the other provides a more sustainable and gentler path. The authors conclude that symptomatic treatment, particularly in patients with stable RA, may be a more cost-effective approach, leading to similar clinical outcomes while minimizing treatment burden and costs.

Navigating the Desert of RA: A Shared Care Approach

This research underscores the importance of individualized treatment approaches for RA, highlighting the need for careful consideration of the patient’s individual needs and preferences. This is like choosing the appropriate path through the desert, considering factors such as the traveler’s experience, resources, and desired destination. The authors suggest that a shared care model, involving both primary care providers and specialists, may be a valuable approach for managing stable RA, allowing for greater flexibility and patient autonomy.

Dr.Camel's Conclusion

This study provides valuable insights into the management of established RA, suggesting that a shared care approach, emphasizing symptom control and patient empowerment, may be a cost-effective and clinically effective option. This research is like finding a sustainable oasis in the desert of RA management, offering a path towards improved patient outcomes and well-being.

Date :
  1. Date Completed 2005-12-30
  2. Date Revised 2019-11-09
Further Info :

Pubmed ID

16153351

DOI: Digital Object Identifier

10.3310/hta9340

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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