Efficacy and safety of rifabutin-containing 'rescue therapy' for resistant Helicobacter pylori infection.

Author: BorodyT J, ClancyR, HerdmanK, LlorenteR, NgC, PangG, SuraceR, WettsteinA R

Paper Details 
Original Abstract of the Article :
BACKGROUND: Current 'rescue' therapies provide inadequate Helicobacter pylori eradication rates because of antibiotic resistance. AIM: To test the efficacy of a modified triple regimen combining rifabutin, pantoprazole and amoxicillin as rescue therapy for patients in whom eradication of H. pylori ...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2036.2006.02793.x

データ提供:米国国立医学図書館(NLM)

Rifabutin-Containing Rescue Therapy: A Desert Oasis for Resistant Helicobacter pylori Infection

The treatment of Helicobacter pylori infection, a common cause of gastritis and ulcers, is often a journey through a desert of antibiotic resistance. This study explores the efficacy of a modified triple regimen containing rifabutin, pantoprazole, and amoxicillin as a rescue therapy for patients who have failed standard clarithromycin-based triple therapy. The researchers found that this rifabutin-containing regimen achieved high eradication rates, even in patients with metronidazole or clarithromycin resistance. This finding provides a potential oasis in the desert of Helicobacter pylori treatment, offering a promising option for patients who have not responded to conventional therapies.

Navigating the Desert of Antibiotic Resistance: A New Treatment Strategy

This study provides a valuable roadmap for navigating the challenges of antibiotic resistance in Helicobacter pylori infection. The researchers' findings demonstrate that a rifabutin-containing regimen can effectively eradicate the bacteria, even in patients with resistance to other commonly used antibiotics. This research offers hope for patients who have not responded to traditional treatments, providing a potential oasis in the desert of antibiotic resistance.

Seeking a Brighter Horizon: Combating Antibiotic Resistance

The study's focus on rifabutin-containing rescue therapy highlights the importance of developing new treatment strategies to combat antibiotic resistance. The researchers' findings demonstrate that rifabutin can be a valuable tool in the fight against resistant Helicobacter pylori infections. This research provides a hopeful glimpse into the future of antibiotic therapy, offering potential solutions for managing the growing challenge of antibiotic resistance.

Dr.Camel's Conclusion

This research offers a valuable oasis in the desert of Helicobacter pylori treatment, highlighting the efficacy of a rifabutin-containing rescue therapy for patients with antibiotic resistance. This study underscores the importance of developing new strategies to combat antibiotic resistance, a growing challenge in the fight against bacterial infections. The findings provide a hopeful glimpse into the future of antibiotic therapy, offering potential solutions for managing this complex and evolving threat.

Date :
  1. Date Completed 2006-06-29
  2. Date Revised 2018-12-03
Further Info :

Pubmed ID

16441468

DOI: Digital Object Identifier

10.1111/j.1365-2036.2006.02793.x

SNS
PICO Info
in preparation
Languages

English

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