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Effect of pain intensity and time to administration on responsiveness to almotriptan: results from AXERT 12.5 mg Time Versus Intensity Migraine Study (AIMS).

Author: , ArmstrongRobert B, DiamondMerle L, ElkindArthur H, FinlaysonGary, FisherAlan C, FreitagFrederick G, GreenbergSteven J, HulihanJoseph F, RapoportAlan M, UngerJeffrey R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Early treatment for migraine headaches was significantly more effective in reducing total headache duration compared to standard treatment. In a cluster-randomized study, patients treated within 1 hour of headache onset, regardless of pain intensity, experienced shorter headache duration. The study also found that treating mild or moderate pain was just as effective as treating severe pain when treatment was initiated within 1 hour.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To determine whether time-based early treatment, independent of pain intensity, is superior to a pain intensity-based treatment, where patients are asked to treat at least moderate intensity headaches, resulting in a reduction of overall migraine headache duration. BACKGROUND: Retrospect...See full text at original site
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引用元：
https://doi.org/10.1111/j.1526-4610.2007.00756.x

データ提供：米国国立医学図書館（NLM）

The Importance of Early Treatment for Migraines

The field of [neurology] is continually searching for ways to effectively treat [migraine headaches]. This research investigates the impact of [time to administration] on the effectiveness of [almotriptan] in reducing [migraine headache duration]. The study compares the outcomes of [early treatment] versus [standard treatment] in patients experiencing [migraine headaches]. The findings emphasize the importance of early intervention in managing [migraine headaches] and the potential benefits of using [almotriptan] at the onset of symptoms.

Early Treatment with Almotriptan Improves Migraine Outcomes

This research demonstrates the potential benefits of [early treatment] with [almotriptan] for [migraine headaches]. The study found that patients who treated their headaches within one hour of onset had significantly shorter [migraine headache duration] compared to those who waited for moderate or severe pain. These findings suggest that early intervention with [almotriptan] may be a more effective approach to managing [migraine headaches].

Managing Migraines Effectively

This research highlights the importance of prompt treatment for [migraine headaches]. The study demonstrates that early intervention with [almotriptan] can significantly reduce [migraine headache duration]. This knowledge empowers individuals to take an active role in managing their [migraine headaches] and seek treatment promptly to minimize the impact of these debilitating episodes.

Dr.Camel's Conclusion

This research explores the impact of [time to administration] on the effectiveness of [almotriptan] in reducing [migraine headache duration]. The study found that early intervention with [almotriptan] was associated with significantly shorter [migraine headache duration]. These findings emphasize the importance of prompt treatment for [migraine headaches] and highlight the potential of [almotriptan] as an effective treatment option.

Date :
  1. Date Completed 2007-06-26
  2. Date Revised 2012-11-15
Further Info :

Pubmed ID

17445101

DOI: Digital Object Identifier

10.1111/j.1526-4610.2007.00756.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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