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Efficacy and safety of aminoglycoside monotherapy: systematic review and meta-analysis of randomized controlled trials.

Author: BorokSara, FraserAbigail, Gafter-GviliAnat, LeiboviciLeonard, PaulMical, VidalLiat

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Aminoglycosides are effective for urinary tract infections, but there is insufficient evidence to recommend their use for other infections.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: This study sought to compare the efficacy and adverse effects of any aminoglycoside as a single antibiotic with other antibiotics for the treatment of patients with infection. METHODS: Systematic review of the literature and meta-analysis. We searched for randomized controlled trials co...See full text at original site
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引用元：
https://doi.org/10.1093/jac/dkm193

データ提供：米国国立医学図書館（NLM）

Aminoglycosides for Urinary Tract Infections: A Meta-Analysis of Their Efficacy and Safety

In the vast desert of medical research, we often encounter oases of valuable knowledge. This study, like a refreshing spring in the midst of a sandy expanse, delves into the efficacy and safety of aminoglycosides for treating infections. It's a meta-analysis, a type of study that combines data from multiple studies to draw a more comprehensive picture. This particular research focuses on urinary tract infections, a common ailment, and compares the effectiveness of aminoglycosides to other antibiotics.

Aminoglycosides: A Suitable Choice for UTI Treatment?

The results of this study, like a guiding star in the night sky, suggest that aminoglycosides are a viable treatment option for urinary tract infections. The analysis indicated that these antibiotics were equally effective as other options in terms of overall survival and treatment success. However, aminoglycosides were associated with a higher rate of bacterial infection after treatment. These findings, like a desert mirage, show both positive and negative aspects to consider.

Understanding the Potential Benefits and Risks

While aminoglycosides might be a good choice for urinary tract infections, we must acknowledge that they can lead to more kidney problems compared to other antibiotics. This is like the shifting sands of the desert, where seemingly safe paths can lead to unexpected dangers. It's crucial to understand these potential risks and weigh them against the potential benefits with your healthcare provider.

Dr. Camel's Conclusion

This research provides valuable insights into the use of aminoglycosides for urinary tract infections. It highlights the importance of considering both efficacy and safety when choosing an antibiotic. As in the desert, where navigation requires careful planning and knowledge of potential hazards, choosing the right antibiotic is crucial for effective and safe treatment.

Date :
  1. Date Completed 2007-11-30
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

17562680

DOI: Digital Object Identifier

10.1093/jac/dkm193

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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