Paper Details

  1. Home
  2. Paper Details

Analysis of pooled data from two pivotal controlled trials on the efficacy of topiramate in the prevention of migraine.

Author: FordeGrace, FreitagFred G, HulihanJoseph, NetoWalter, SchmittJennifer, WangDaniel Z, WuShu-Chen

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Many people with migraine headaches should receive preventive treatment due to how often they have migraines and how disabling they are. This study examines the use of the anticonvulsant topiramate in two large, controlled trials for patients experiencing 3-12 migraine headaches per month.
Paper Details　
Original Abstract of the Article :
A substantial proportion of the patient population with migraine headache should be considered for preventive treatment based on the frequency and disability associated with this disorder. Use of the anticonvulsant topiramate was previously examined in two large, double-blind, randomized, placebo-co...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/17682112

データ提供：米国国立医学図書館（NLM）

Preventing Migraines: A Look at the Efficacy of Topiramate

The debilitating nature of migraine headaches affects a significant portion of the population, often leading to significant disability. This research examines the effectiveness of topiramate, an anticonvulsant medication, in preventing migraine headaches. The study analyzed pooled data from two large, double-blind, randomized, placebo-controlled clinical trials, providing a comprehensive assessment of topiramate's efficacy.

Topiramate's Promise: A Potential Migraine Prevention Tool

The study's findings suggest that topiramate may be an effective preventive treatment for migraine headaches, particularly for individuals experiencing 3 to 12 episodes per month. While further research is needed to fully elucidate the mechanisms underlying topiramate's efficacy, these findings offer a promising avenue for migraine prevention.

Living with Migraines: Exploring Treatment Options

This research highlights the importance of exploring preventive treatment options for migraine sufferers. Topiramate, along with other potential preventive therapies, may offer relief from the chronic burden of migraine headaches, improving the quality of life for many individuals.

Dr. Camel's Conclusion

This study provides valuable evidence for the potential of topiramate as a migraine preventive treatment. It emphasizes the importance of proactive management strategies for migraine headaches, empowering individuals to seek out effective therapies and maintain their overall well-being.

Date :
  1. Date Completed 2007-09-25
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

17682112

DOI: Digital Object Identifier

107/7/251

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.