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A meta-analysis on the efficacy of oral theophylline in patients with stable COPD.

Author: MolfinoNéstor A, ZhangPeter

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

This study evaluates the efficacy of oral theophylline, a nonspecific phosphodiesterase inhibitor, in patients with clinically stable COPD. The study aimed to measure improvements in FEV1 and FVC, two indicators of lung function.
Paper Details　
Original Abstract of the Article :
Theophylline is a nonspecific inhibitor of phosphodiesterases that, despite exerting bronchodilator and anti-inflammatory effects, is a third-line therapy rarely used to treat chronic airflow limitation. We wished to evaluate the efficacy of oral theophylline as measured by improvements in trough (p...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707158/

データ提供：米国国立医学図書館（NLM）

Evaluating the Efficacy of Oral Theophylline in Stable COPD

This research explores the field of [respiratory medicine] and [chronic obstructive pulmonary disease (COPD)], evaluating the efficacy of oral theophylline, a medication used to treat COPD. The researchers conducted a [meta-analysis] of existing studies to assess the effectiveness of oral theophylline in patients with stable COPD. The study found that [oral theophylline was associated with modest improvements in lung function], but it was not considered a first-line treatment for COPD.

Theophylline in COPD Treatment

The study's findings suggest that [oral theophylline may have a limited role in managing COPD symptoms]. The researchers recommend that [theophylline be considered as a third-line treatment option] after other therapies have been tried.

Navigating the Desert of Lung Disease

Just as a camel can traverse the vast desert, our respiratory system is constantly working to ensure that we can breathe easily. This research highlights the complexity of COPD and the ongoing search for effective treatment options.

Dr.Camel's Conclusion

This study provides valuable insights into the efficacy of oral theophylline for COPD. While theophylline may offer modest benefits, the study's findings suggest that it is not a first-line treatment option.

Date :
  1. Date Completed 2008-01-11
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18046863

DOI: Digital Object Identifier

PMC2707158

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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