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A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: 2008 update.

Author: DieterichDouglas T, HanSteven-Huy B, JacobsonIra M, KeeffeEmmet B, MartinPaul, SchiffEugene R, TobiasHillel

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Practice GuidelineGuidelines and recommendations for the diagnosis and treatment of specific medical conditions in medical practice.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Chronic hepatitis B infection is a major health issue globally and in the US. Treatment guidelines for hepatitis B have been updated based on new research, improved testing, and new medications. The goal of treatment is to reduce the levels of hepatitis B virus in the blood to very low or undetectable levels. Several medications are available, but entecavir, peginterferon alfa-2a, and tenofovir are preferred first-line options. The choice of medication depends on factors like effectiveness, safety, the risk of resistance, how the medication is given, and cost.
Paper Details　
Original Abstract of the Article :
Chronic HBV infection is an important public health problem worldwide and in the United States. A treatment algorithm for the management of this disease, published previously by a panel of U.S. hepatologists, has been revised on the basis of new developments in the understanding of the disorder, the...See full text at original site
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引用元：
https://doi.org/10.1016/j.cgh.2008.08.021

データ提供：米国国立医学図書館（NLM）

Chronic Hepatitis B: A Treatment Algorithm

The field of [Hepatitis B treatment] has evolved over time, and this research tackles a crucial issue within it. The researchers utilized a [Systematic review of the literature] approach to develop a [Treatment algorithm for chronic hepatitis B]. They identified [New treatments and diagnostic tests] that have transformed the landscape of this disease. A key finding is that [Specific treatments like entecavir, peginterferon alfa-2a, and tenofovir] have emerged as preferred first-line therapies. Their evaluation considered [Efficacy, safety, resistance, administration, and cost] to optimize treatment outcomes.

Understanding the Algorithm's Impact

This updated algorithm provides valuable guidance for [Physicians and healthcare professionals] managing chronic hepatitis B. It highlights the [Importance of monitoring serum HBV DNA levels] to track treatment effectiveness and identify drug resistance. This research emphasizes the [Continual need for research and development] in this area to further improve treatment strategies.

Living with Chronic Hepatitis B

The development of new therapies like those discussed in this research offers hope for patients struggling with [Chronic hepatitis B]. It underscores the significance of [Following medical advice and engaging in regular monitoring] for optimal management of the disease.

Dr.Camel's Conclusion

This research, like a compass in the vast desert of medical knowledge, guides us toward more effective management of chronic hepatitis B. The algorithm, a beacon of hope for patients and healthcare professionals, illuminates a path toward better treatment outcomes. However, like a sandstorm, the challenges of drug resistance and the need for further research remain a constant reminder that our journey in understanding this complex disease continues.

Date :
  1. Date Completed 2009-02-04
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

18845489

DOI: Digital Object Identifier

10.1016/j.cgh.2008.08.021

SNS
PICO Info
in preparation
Languages

English

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